PA5-27875 targets FRS2 in WB applications and shows reactivity with Human samples.
The PA5-27875 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 232 of Human FRS2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
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Protein Aliases: FGFR signalling adaptor; FGFR substrate 2; FGFR-signaling adaptor SNT; Fibroblast growth factor receptor substrate 2; FRS2-alpha; FRS2A; FRS2alpha; SNT; SNT-1; SNT1; Suc1-associated neurotrophic factor target 1
Gene Aliases: 4732458E18; C330018A15Rik; FRS1A; FRS2; FRS2A; FRS2alpha; SNT; SNT-1; SNT1