Proteintech

FSTL1 Polyclonal Antibody

View all (19) FSTL1 antibodies

Questions & Answers

Questions & Answers

Product Image Gallery

FSTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human placenta tissue slide using 20182-1-AP ( FSTL1 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

FSTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human placenta tissue slide using 20182-1-AP ( FSTL1 antibody) at dilution of 1:200 (under 10x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

FSTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human pancreas tissue slide using 20182-1-AP (FSTL1 Antibody) at dilution of 1:50 (under 40x lens).

FSTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human pancreas tissue slide using 20182-1-AP (FSTL1 Antibody) at dilution of 1:50 (under 10x lens).

FSTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human gliomas tissue slide using 20182-1-AP (FSTL1 Antibody) at dilution of 1:50 (under 40x lens).

FSTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human gliomas tissue slide using 20182-1-AP (FSTL1 Antibody) at dilution of 1:50 (under 10x lens).

FSTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded rat testis tissue slide using 20182-1-AP (FSTL1 Antibody) at dilution of 1:200 (under 40x lens).

FSTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded rat testis tissue slide using 20182-1-AP (FSTL1 Antibody) at dilution of 1:200 (under 10x lens).

FSTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded rat colon tissue slide using 20182-1-AP (FSTL1 Antibody) at dilution of 1:200 (under 40x lens).

FSTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded rat colon tissue slide using 20182-1-AP (FSTL1 Antibody) at dilution of 1:200 (under 10x lens).

FSTL1 Antibody in Western Blot (WB) — Human placenta tissue were subjected to SDS PAGE followed by western blot with 20182-1-AP ( FSTL1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

FSTL1 Antibody in Western Blot (WB) — A2780 cells were subjected to SDS PAGE followed by western blot with 20182-1-AP (FSTL1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

FSTL1 Antibody in Immunoprecipitation (IP) — IP result of anti-FSTL1 (IP:20182-1-AP, 4 ug; Detection:20182-1-AP 1:500) with A2780 cells lysate 960 ug.

Product Details

20182-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	View 5 publications 5 publications
Immunohistochemistry (IHC)	-	View 3 publications 3 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:50-1:500	-
Immunocytochemistry (ICC/IF)	-	View 1 publication 1 publication
Immunoprecipitation (IP)	Assay-dependent	-

Product Specifications
Species Reactivity	Human, Rat
Published species	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	FSTL1 Fusion Protein Ag14057 (1-308 aa encoded by BC000055) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.35 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MWKRWLALA LALVAVAWVR AEEELRSKSK ICANVFCGAG RECAVTEKGE PTCLCIEQCK PHKRPVCGSN GKTYLNHCEL HRDACLTGSK IQVDYDGHCK EKKSVSPSAS PVVCYQSNRD ELRRRIIQWL EAEIIPDGWF SKGSNYSEIL DKYFKNFDNG DSRLDSSEFL KFVEQNETAI NITTYPDQEN NKLLRGLCVD ALIELSDENA DWKLSFQEFL KCLNPSFNPP EKKCALEDET YADGAETEVD CNRCVCACGN WVCTAMTCDG KNQKGAQTQT EEEMTRYVQE LQKHQETAEK TKRVSTKEI (1-308 aa encoded by BC000055 )

Target Information

This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

FSTL1 interacts with VIM and promotes colorectal cancer metastasis via activating the focal adhesion signalling pathway.

Cell death & disease

Gu C,Wang X,Long T,Wang X,Zhong Y,Ma Y,Hu Z,Li Z

Tue May 29 00:00:00 EDT 2018

FSTL1 interacts with VIM and promotes colorectal cancer metastasis via activating the focal adhesion signalling pathway.

Cell death & disease

Gu C,Wang X,Long T,Wang X,Zhong Y,Ma Y,Hu Z,Li Z

Tue May 29 00:00:00 EDT 2018

EGF hijacks miR-198/FSTL1 wound-healing switch and steers a two-pronged pathway toward metastasis.

The Journal of experimental medicine

Sundaram GM,Ismail HM,Bashir M,Muhuri M,Vaz C,Nama S,Ow GS,Vladimirovna IA,Ramalingam R,Burke B,Tanavde V,Kuznetsov V,Lane EB,Sampath P

Mon Oct 02 00:00:00 EDT 2017

EGF hijacks miR-198/FSTL1 wound-healing switch and steers a two-pronged pathway toward metastasis.

The Journal of experimental medicine

Sundaram GM,Ismail HM,Bashir M,Muhuri M,Vaz C,Nama S,Ow GS,Vladimirovna IA,Ramalingam R,Burke B,Tanavde V,Kuznetsov V,Lane EB,Sampath P

Mon Oct 02 00:00:00 EDT 2017

Decrease of FSTL1-BMP4-Smad signaling predicts poor prognosis in lung adenocarcinoma but not in squamous cell carcinoma.

Scientific reports

Chiou J,Su CY,Jan YH,Yang CJ,Huang MS,Yu YL,Hsiao M

Tue Aug 29 00:00:00 EDT 2017

Decrease of FSTL1-BMP4-Smad signaling predicts poor prognosis in lung adenocarcinoma but not in squamous cell carcinoma.

Scientific reports

Chiou J,Su CY,Jan YH,Yang CJ,Huang MS,Yu YL,Hsiao M

Tue Aug 29 00:00:00 EDT 2017

Apical Secretion of FSTL1 in the Respiratory Epithelium for Normal Lung Development.

PloS one

Li X,Fang Y,Li X,Liang J,Jiang D,Geng Y,Ning W

Mon Jul 17 00:00:00 EDT 2017

Apical Secretion of FSTL1 in the Respiratory Epithelium for Normal Lung Development.

PloS one

Li X,Fang Y,Li X,Liang J,Jiang D,Geng Y,Ning W

Mon Jul 17 00:00:00 EDT 2017

Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation.

Journal of proteomics

Chen SX,Xu XE,Wang XQ,Cui SJ,Xu LL,Jiang YH,Zhang Y,Yan HB,Zhang Q,Qiao J,Yang PY,Liu F

Tue Oct 14 00:00:00 EDT 2014

Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation.

Journal of proteomics

Chen SX,Xu XE,Wang XQ,Cui SJ,Xu LL,Jiang YH,Zhang Y,Yan HB,Zhang Q,Qiao J,Yang PY,Liu F

Tue Oct 14 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: FLJ50214; FLJ52277; follistatin-like 1; Follistatin-like protein 1; Follistatin-related protein 1

Gene Aliases: FRP; FSL1; Fstl; FSTL1; MIR198; OCC-1; OCC1; tsc36

UniProt ID: (Human) Q12841, (Rat) Q62632

Entrez Gene ID: (Human) 11167, (Rat) 79210

Molecular Function: protease inhibitor

BMP signaling pathway response to starvation

Process(es)

calcium ion binding protein binding heparin binding