Search
Agrisera
FTIP3/FTIP4/FT Interacting Protein 3/4 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 1
FTIP3/FTIP4/FT Interacting Protein 3/4 Antibody (AS23-5001) in WB
Samples: mctp 3 mctp 4 - Arabidopsis thaliana double knockout mutant mctp 3 - Arabidopsis thaliana single knockout mutant mctp 4 - Arabidopsis thaliana single knockout mutant Wild type - Arabidopsis thaliana wild type 10 µg od protein/well of total protein extracted freshly from 7 days old Arabidopsis thaliana seedlings. Exact buffer components were 150 m M Tris-HCl, p H 7.5; 150 m M Na Cl; 10% glycerol; 10... View More
Product Details
AS23-5001
Product Specifications
Species Reactivity
Plant
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
KLH-conjugated peptide derived from Arabidopsis thaliana protein sequences of MCTP3 and MCTP4.
Conjugate
Form
Lyophilized
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
Target Information
FTIP3 and FTIP4 encode Arabidopsis multiple C2 domain and transmembrane region (MCTP)-type proteins that localize to endomembrane compartments and function in the shoot apical meristem (SAM) to control intracellular protein trafficking critical for stem cell maintenance. Structurally, both proteins are characterized by multiple N-terminal C2 domains (consistent with Ca2+-dependent membrane/lipid binding) coupled to C-terminal transmembrane region(s) that anchor them to membranes, supporting roles as membrane-tethered trafficking regulators rather than soluble transcriptional factors. Biologically, FTIP3/4 act to restrain aberrant delivery of the homeobox regulator SHOOTMERISTEMLESS (STM) to the plasma membrane in peripheral SAM cells, thereby favoring STM recycling/retention in the nucleus where it sustains meristematic identity; loss of FTIP3/4 shifts STM toward plasma-membrane accumulation, enhances intercellular trafficking at the expense of nuclear localization, and accelerates stem cell differentiation with premature shoot apex termination and dwarf, bushy architecture.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: FTIP3; FTIP4; MCTP3; MCTP4
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support