FIGURE: 1 / 2
FUCA2 (Alpha-L-fucosidase) catalyzes the hydrolysis of terminal alpha-L-fucosidase linkages in glycosphingolipids and glycoproteins. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man. The FUCA2 locus regulates the level of alpha-fucosidase in plasma and fibroblasts but not in leukocytes. In fucosidosis, deficiency of alpha-L-fucosidase is found in both plasma and leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-L-fucosidase 2; Alpha-L-fucoside fucohydrolase 2; MGC1314; Plasma alpha-L-fucosidase
Gene Aliases: dJ20N2.5; FUCA2; PSEC0151; UNQ227/PRO260
UniProt ID: (Human) Q9BTY2
Entrez Gene ID: (Human) 2519
Molecular Function: glycosidase