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Product Details
22141-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,500 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:20-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
FUT4 Fusion Protein Ag17565 (174-407 aa encoded by BC136374) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.46 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
22141-1-AP detects the band around 45 kDa and glycosylated isoform 63 kDa protein in SDS-PAGE.
Immunogen sequence: QLPPLPWAS PTPSRPVGVL LWWEPFGGRD SAPRPPPDCR LRFNISGCRL LTDRASYGEA QAVLFHHRDL VKGPPDWPPP WGIQAHTAEE VDLRVLDYEE AAAAAEALAT SSPRPPGQRW VWMNFESPSH SPGLRSLASN LFNWTLSYRA DSDVFVPYGY LYPRSHPGDP PSGLAPPLSR KQGLVAWVVS HWDERQARVR YYHQLSQHVT VDVFGRGGPG QPVPEIGLLH TVARY (174-407 aa encoded by BC136374)
Target Information
FUT4 (Fucosyltransferase 4) is a Protein Coding gene. Diseases associated with FUT4 include Colon Adenocarcinoma and Liver Lymphoma. Among its related pathways are Glycosphingolipid biosynthesis - lacto and neolacto series and Mannose type O-glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include fucosyltransferase activity and alpha-(1->3)-fucosyltransferase activity. The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; alpha (1,3) fucosyltransferase, myeloid-specific; Alpha-(1,3)-fucosyltransferase 4; ELAM ligand fucosyltransferase; ELAM-1 ligand fucosyltransferase; Fuc-TIV; Fucosyltransferase 4; fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific); Fucosyltransferase IV; fucT-IV; Galactoside 3-L-fucosyltransferase; Lewis X; stage-specific embryonic antigen 1
Gene Aliases: CD15; ELFT; FCT3A; FUC-TIV; FUT4; FUTIV; LeX; SSEA-1
UniProt ID: (Human) P22083
Entrez Gene ID: (Human) 2526
Molecular Function:
glycosyltransferase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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