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Proteintech
FXR2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
12552-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FXR2 Fusion Protein Ag3402 (1-354 aa encoded by BC020090)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGGLASGGD VEPGLPVEVR GSNGAFYKGF VKDVHEDSVT IFFENNWQSE RQIPFGDVRL PPPADYNKEI TEGDEVEVYS RANEQEPCGW WLARVRMMKG DFYVIEYAAC DATYNEIVTL ERLRPVNPNP LATKGSFFKV TMAVPEDLRE ACSNENVHKE FKKALGANCI FLNITNSELF ILSTTEAPVK RASLLGDMHF RSLRTKLLLM SRNEEATKHL ETSKQLAAAF QEEFTVREDL MGLAIGTHGA NIQQARKVPG VTAIELGEET CTFRIYGETP EACRQARSYL EFSEDSVQVP RNLVGKVIGK NGKVIQEIVD KSGVVRVRVE GDNDKKNPRE EGMVPFIFVG TRENI (1-354 aa encoded by BC020090)
Target Information
Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Fxr2h; unnamed protein product
Gene Aliases: FMR1L2; Fxr2h; FXR2P
UniProt ID: (Human) P51116
Entrez Gene ID: (Human) 9513, (Mouse) 23879
regulation of translation
posttranscriptional regulation of gene expression
negative regulation of gene expression
dentate gyrus development
regulation of mRNA stability
positive regulation of translation
positive regulation of long-term neuronal synaptic plasticity
animal organ development
mRNA transport
mRNA destabilization
regulation of translation at presynapse, modulating synaptic transmission
regulation of mRNA metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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