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Invitrogen
FZD6 Polyclonal Antibody
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FIGURE: 1 / 1
FZD6 Antibody (720414) in WB
Western blot analysis was performed on Membrane enriched extracts (30 µg lysate) of Hep G2 (Lane 1), T-47D (Lane 2), SH-SY5Y (Lane 3), HT-29 (Lane 4) and SW480 (Lane 5). The blots were probed with Anti-Frizzled 6 Rabbit Polyclonal Antibody (Product # 720414, 2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.2 µg/mL, 1:5000 dilution). A 79 kDa band corresponding to Frizzled 6 was observed across the cell lines tested. Known quantity of prot... View More
Product Details
720414
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Protein corresponding to human FZD6 [aa19-aa201]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 30% glycerol, 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with Monkey, Horse, Rabbit.
Target Information
The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: frizzled 6, seven transmembrane spanning receptor; frizzled family receptor 6; frizzled homolog 6; Frizzled-6; Frizzled6; Fz-6; FZD-6; seven transmembrane helix receptor
Gene Aliases: FZ-6; FZ6; FZD6; HFZ6; NDNC10
UniProt ID: (Human) O60353
Entrez Gene ID: (Human) 8323
establishment of planar polarity
neural tube closure
hair follicle development
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
platelet activation
cell proliferation in midbrain
non-canonical Wnt signaling pathway
embryonic nail plate morphogenesis
inner ear morphogenesis
negative regulation of sequence-specific DNA binding transcription factor activity
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
midbrain morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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