Coagulation factor IX is a single chain polypeptide with a molecular mass of 57 kDa. Normal concentrations of factor IX in human plasma is approximately 3 µg/mL. Factor IX deficiency and lack of coagulation activity is seen in patients suffering from the innate X-chromosome linked disorder, hemophilia B.
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Protein Aliases: Christmas factor; coagulation factor 9; Coagulation factor IX; Coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B); Coagulation factor IXa heavy chain; Coagulation factor IXa light chain; F9; factor 9; factor IX F9; plasma thromboplastic component; Plasma thromboplastin component; PTC
Gene Aliases: AW111646; Cf-9; Cf9; F9; F9 p22; FIX; HEMB; P19; PTC; THPH8
Molecular Function: annexin calcium-binding protein calmodulin enzyme modulator hydrolase intracellular calcium-sensing protein peptide hormone protease protease inhibitor receptor serine protease signaling molecule