This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
Recommended positive controls: human liver, mouse liver, rat liver, HCT116.
Predicted reactivity: Mouse (94%), Rat (96%), Dog (96%), Cat (96%), Pig (87%), Chicken (93%), Sheep (93%), Rhesus Monkey (99%), Bovine (92%), Guinea pig (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apoferritin; Cell proliferation-inducing gene 15 protein; Ferritin H subunit; Ferritin heavy chain; ferritin heavy chain 1; Ferritin heavy chain, N-terminally processed; Ferritin subunit H; ferritin, heavy polypeptide 1; frih; H-ferritin; MGC104426; placenta immunoregulatory factor; proliferation-inducing protein 15
Gene Aliases: FHC; FTH; FTH1; FTHL6; HFE5; HFt; MFH; OK/SW-cl.84; PIG15; PLIF
Molecular Function: storage protein