Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MQWTSLLLL AGLFSLSQAQ YEDDPHWWFH YLRSQQSTYY DPYDPYPYET YEPYPYGVDE GPAYTYGSPS PPDPRDCPQE CDCPPNFPTA MYCDNRNLKY LPFVPSRMKY VYFQNNQITS IQEGVFDNAT GLLWIALHGN QITSDKVGRK VFSKLRHLER LYLDHNNLTR MPGPLPRSLR ELHLDHNQIS RVPNNALEGL ENLTALYLQH NEIQEVGSSM RGLRSLILLD LSYNHLRKVP DGLPSALEQL YMEHNNVYTV PDSYFRGAPK LLYVRLSHNS LTNNGLASNT FNSSSLLELD LSYNQLQKIP PVNTNLENLY LQGNRINEFS ISSFCTVVDV VNFSKLQVLR LDGNEIKRSA MPADAPLCLR LASLIEI (1-376 aa encoded by BC035281)
Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Collagen-binding 59 kDa protein; Fibromodulin; FM; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin
Gene Aliases: AI131919; AU041740; FM; FMOD; SLRR2E
UniProt ID: (Human) Q06828, (Mouse) P50608, (Rat) P50609
Entrez Gene ID: (Human) 2331, (Mouse) 14264, (Rat) 64507
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