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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 19-376 of human FMOD (NP_002014.2). |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1.99 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2855144 |
Sequence of this protein is as follows: QYEDDPHWWF HYLRSQQSTY YDPYDPYPYE TYEPYPYGVD EGPAYTYGSP SPPDPRDCPQ ECDCPPNFPT AMYCDNRNLK YLPFVPSRMK YVYFQNNQIT SIQEGVFDNA TGLLWIALHG NQITSDKVGR KVFSKLRHLE RLYLDHNNLT RMPGPLPRSL RELHLDHNQI SRVPNNALEG LENLTALYLQ HNEIQEVGSS MRGLRSLILL DLSYNHLRKV PDGLPSALEQ LYMEHNNVYT VPDSYFRGAP KLLYVRLSHN SLTNNGLASN TFNSSSLLEL DLSYNQLQKI PPVNTNLENL YLQGNRINEF SISSFCTVVD VVNFSKLQVL RLDGNEIKRS AMPADAPLCL RLASLIEI
Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Collagen-binding 59 kDa protein; Fibromodulin; FM; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin
Gene Aliases: AI131919; AU041740; FM; FMOD; SLRR2E
UniProt ID: (Human) Q06828, (Mouse) P50608, (Rat) P50609
Entrez Gene ID: (Human) 2331, (Mouse) 14264, (Rat) 64507
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