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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 172 and 376 of Human Fibromodulin|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27796 targets Fibromodulin in WB applications and shows reactivity with Human samples.
The PA5-27796 immunogen is recombinant fragment corresponding to a region within amino acids 172 and 376 of Human Fibromodulin.
Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
collagen-binding 59 kDa protein; fibromodulin proteoglycan; keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin; SLRR2E
FM; FMOD; SLRR2E