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Invitrogen
Folate Receptor alpha Polyclonal Antibody
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FIGURE: 1 / 4
Folate Receptor alpha Antibody (PA5-24186) in IHC (P)
Immunohistochemistry analysis of Folate Receptor alpha in paraffin-embedded Human kidney tissue. Samples were incubated with Folate Receptor alpha polyclonal antibody (Product # PA5-24186) using a dilution of 1:1,000 for 1 hours at room temperature followed by an undiluted biotinylated CRF Anti-Polyvalent HRP Polymer antibody.
Product Details
PA5-24186
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 33-68 amino acids from the N-terminal region of human FOLR1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
200 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adult folate-binding protein; FBP; folate binding protein; Folate receptor 1; folate receptor 1 (adult); Folate receptor alpha; Folate receptor, adult; folate-binding protein precursor; FOLR1; FR-alpha; KB cells FBP; MOv18; Ovarian tumor-associated antigen MOv18
Gene Aliases: FBP; FOLR; FOLR1; FRalpha; NCFTD
UniProt ID: (Human) P15328
Entrez Gene ID: (Human) 2348
heart looping
neural crest cell migration involved in heart formation
cardiac neural crest cell migration involved in outflow tract morphogenesis
receptor-mediated endocytosis
cell adhesion
fusion of sperm to egg plasma membrane
folic acid transport
regulation of transforming growth factor beta receptor signaling pathway
axon regeneration
sperm-egg recognition
tetrahydrofolate biosynthetic process
folic acid metabolic process
response to axon injury
regulation of canonical Wnt signaling pathway
pharyngeal arch artery morphogenesis
anterior neural tube closure
cellular response to folic acid
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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