The target sequence has 95% sequence homology with canine, 92% sequence homology with rat and 91% sequence homology with bovine.
This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X.
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Protein Aliases: BHD skin lesion fibrofolliculoma protein; Birt-Hogg-Dube syndrome protein; Folliculin
Gene Aliases: AU014660; B430214A04Rik; BHD; FLCL; FLCN