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Invitrogen
Fractin Polyclonal Antibody
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Product Details
PA5-95652
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acid residues from the C terminal region of the 32-kDa actin fragment
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is specific for endogenous levels of the ~32 kDa fractin protein and shows no reactivity toward intact actin. There is often a ladder of smaller bands in cells or culture or in-vivo preparations due to further degradation by other proteases. In IHC, the antibody detects the processes and cell bodies of degenerating neurons and plaque-associated microglia in Alzheimer's disease.
Target Information
Fractin (fragment of actin) is a caspase-specific cleavage product of actin and serves as a novel marker of apoptosis-related events. It has recently been reported that fractin may have a functional role in apoptotic signaling in oligodendrocytes (Schulz, R., et al., Glia, 2009).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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