Product References
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas.
Cancer discovery
Cervia LD,Shibue T,Borah AA,Gaeta B,He L,Leung L,Li N,Moyer SM,Shim BH,Dumont N,Gonzalez A,Bick NR,Kazachkova M,Dempster JM,Krill-Burger JM,Piccioni F,Udeshi ND,Olive ME,Carr SA,Root DE,McFarland JM,Vazquez F,Hahn WC
Wed Mar 01 00:00:00 EST 2023
Stress granules affect the sensitivity of renal cancer cells to sorafenib by sequestering and stabilizing COX‑2 mRNA.
Oncology letters
Dai H,Wang G,Cao W,Qi W,Chen W,Guo H
Thu Jun 01 00:00:00 EDT 2023
Stress granules affect the sensitivity of renal cancer cells to sorafenib by sequestering and stabilizing COX‑2 mRNA.
Oncology letters
Dai H,Wang G,Cao W,Qi W,Chen W,Guo H
Thu Jun 01 00:00:00 EDT 2023
Effect of P53 nuclear localization mediated by G3BP1 on ferroptosis in acute liver failure.
Apoptosis : an international journal on programmed cell death
Li W,Li W,Li X,Wang L,Wang Y
Tue Aug 01 00:00:00 EDT 2023
Identification and validation of a novel stress granules-related prognostic model in colorectal cancer.
Frontiers in genetics
Liu Z,Zhao E,Li H,Lin D,Huang C,Zhou Y,Zhang Y,Pan X,Liao W,Li F
Mon May 22 00:00:00 EDT 2023
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Developmental cell
Geng J,Khaket TP,Pan J,Li W,Zhang Y,Ping Y,Cobos Sillero MI,Lu B
Mon Apr 10 00:00:00 EDT 2023
Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules.
Cell reports
McGoldrick P,Lau A,You Z,Durcan TM,Robertson J
Tue Mar 28 00:00:00 EDT 2023
African swine fever virus pS273R antagonizes stress granule formation by cleaving the nucleating protein G3BP1 to facilitate viral replication.
The Journal of biological chemistry
Li T,Li X,Wang X,Chen X,Zhao G,Liu C,Bao M,Song J,Li J,Huang L,Rong J,Tian K,Deng J,Zhu J,Cai X,Bu Z,Zheng J,Weng C
Sat Jul 01 00:00:00 EDT 2023
African swine fever virus pS273R antagonizes stress granule formation by cleaving the nucleating protein G3BP1 to facilitate viral replication.
The Journal of biological chemistry
Li T,Li X,Wang X,Chen X,Zhao G,Liu C,Bao M,Song J,Li J,Huang L,Rong J,Tian K,Deng J,Zhu J,Cai X,Bu Z,Zheng J,Weng C
Sat Jul 01 00:00:00 EDT 2023
Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules.
Cell
Cui Q,Bi H,Lv Z,Wu Q,Hua J,Gu B,Huo C,Tang M,Chen Y,Chen C,Chen S,Zhang X,Wu Z,Lao Z,Sheng N,Shen C,Zhang Y,Wu ZY,Jin Z,Yang P,Liu H,Li J,Bai G
Thu Feb 16 00:00:00 EST 2023
Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules.
Cell
Cui Q,Bi H,Lv Z,Wu Q,Hua J,Gu B,Huo C,Tang M,Chen Y,Chen C,Chen S,Zhang X,Wu Z,Lao Z,Sheng N,Shen C,Zhang Y,Wu ZY,Jin Z,Yang P,Liu H,Li J,Bai G
Thu Feb 16 00:00:00 EST 2023
Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules.
Cell
Cui Q,Bi H,Lv Z,Wu Q,Hua J,Gu B,Huo C,Tang M,Chen Y,Chen C,Chen S,Zhang X,Wu Z,Lao Z,Sheng N,Shen C,Zhang Y,Wu ZY,Jin Z,Yang P,Liu H,Li J,Bai G
Thu Feb 16 00:00:00 EST 2023
Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules.
Cell
Cui Q,Bi H,Lv Z,Wu Q,Hua J,Gu B,Huo C,Tang M,Chen Y,Chen C,Chen S,Zhang X,Wu Z,Lao Z,Sheng N,Shen C,Zhang Y,Wu ZY,Jin Z,Yang P,Liu H,Li J,Bai G
Thu Feb 16 00:00:00 EST 2023
Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules.
Cell
Cui Q,Bi H,Lv Z,Wu Q,Hua J,Gu B,Huo C,Tang M,Chen Y,Chen C,Chen S,Zhang X,Wu Z,Lao Z,Sheng N,Shen C,Zhang Y,Wu ZY,Jin Z,Yang P,Liu H,Li J,Bai G
Thu Feb 16 00:00:00 EST 2023
Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules.
Cell
Cui Q,Bi H,Lv Z,Wu Q,Hua J,Gu B,Huo C,Tang M,Chen Y,Chen C,Chen S,Zhang X,Wu Z,Lao Z,Sheng N,Shen C,Zhang Y,Wu ZY,Jin Z,Yang P,Liu H,Li J,Bai G
Thu Feb 16 00:00:00 EST 2023
Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure.
World journal of gastroenterology
Li WY,Yang F,Li X,Wang LW,Wang Y
Tue Feb 28 00:00:00 EST 2023
Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure.
World journal of gastroenterology
Li WY,Yang F,Li X,Wang LW,Wang Y
Tue Feb 28 00:00:00 EST 2023
Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure.
World journal of gastroenterology
Li WY,Yang F,Li X,Wang LW,Wang Y
Tue Feb 28 00:00:00 EST 2023
Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure.
World journal of gastroenterology
Li WY,Yang F,Li X,Wang LW,Wang Y
Tue Feb 28 00:00:00 EST 2023
The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation.
Cell reports
Curdy N,Lanvin O,Cerapio JP,Pont F,Tosolini M,Sarot E,Valle C,Saint-Laurent N,Lhuillier E,Laurent C,Fournié JJ,Franchini DM
Tue Mar 28 00:00:00 EDT 2023
The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation.
Cell reports
Curdy N,Lanvin O,Cerapio JP,Pont F,Tosolini M,Sarot E,Valle C,Saint-Laurent N,Lhuillier E,Laurent C,Fournié JJ,Franchini DM
Tue Mar 28 00:00:00 EDT 2023
The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation.
Cell reports
Curdy N,Lanvin O,Cerapio JP,Pont F,Tosolini M,Sarot E,Valle C,Saint-Laurent N,Lhuillier E,Laurent C,Fournié JJ,Franchini DM
Tue Mar 28 00:00:00 EDT 2023
Integrative genetic analysis illuminates ALS heritability and identifies risk genes.
Nature communications
Megat S,Mora N,Sanogo J,Roman O,Catanese A,Alami NO,Freischmidt A,Mingaj X,De Calbiac H,Muratet F,Dirrig-Grosch S,Dieterle S,Van Bakel N,Müller K,Sieverding K,Weishaupt J,Andersen PM,Weber M,Neuwirth C,Margelisch M,Sommacal A,Van Eijk KR,Veldink JH,Lautrette G,Couratier P,Camuzat A,Le Ber I,Grassano M,Chio A,Boeckers T,Ludolph AC,Roselli F,Yilmazer-Hanke D,Millecamps S,Kabashi E,Storkebaum E,Sellier C,Dupuis L
Fri Jan 20 00:00:00 EST 2023
Integrative genetic analysis illuminates ALS heritability and identifies risk genes.
Nature communications
Megat S,Mora N,Sanogo J,Roman O,Catanese A,Alami NO,Freischmidt A,Mingaj X,De Calbiac H,Muratet F,Dirrig-Grosch S,Dieterle S,Van Bakel N,Müller K,Sieverding K,Weishaupt J,Andersen PM,Weber M,Neuwirth C,Margelisch M,Sommacal A,Van Eijk KR,Veldink JH,Lautrette G,Couratier P,Camuzat A,Le Ber I,Grassano M,Chio A,Boeckers T,Ludolph AC,Roselli F,Yilmazer-Hanke D,Millecamps S,Kabashi E,Storkebaum E,Sellier C,Dupuis L
Fri Jan 20 00:00:00 EST 2023
circIPO7 dissociates caprin-1 from ribosomes and inhibits gastric cancer cell proliferation by suppressing EGFR and mTOR.
Oncogene
Liu J,Niu L,Hao J,Yao Y,Yan M,Li H
Wed Mar 01 00:00:00 EST 2023
circIPO7 dissociates caprin-1 from ribosomes and inhibits gastric cancer cell proliferation by suppressing EGFR and mTOR.
Oncogene
Liu J,Niu L,Hao J,Yao Y,Yan M,Li H
Wed Mar 01 00:00:00 EST 2023
Canonical cellular stress granules are required for arsenite-induced necroptosis mediated by Z-DNA-binding protein 1.
Science signaling
Szczerba M,Johnson B,Acciai F,Gogerty C,McCaughan M,Williams J,Kibler KV,Jacobs BL
Tue Mar 14 00:00:00 EDT 2023
Canonical cellular stress granules are required for arsenite-induced necroptosis mediated by Z-DNA-binding protein 1.
Science signaling
Szczerba M,Johnson B,Acciai F,Gogerty C,McCaughan M,Williams J,Kibler KV,Jacobs BL
Tue Mar 14 00:00:00 EDT 2023
Canonical cellular stress granules are required for arsenite-induced necroptosis mediated by Z-DNA-binding protein 1.
Science signaling
Szczerba M,Johnson B,Acciai F,Gogerty C,McCaughan M,Williams J,Kibler KV,Jacobs BL
Tue Mar 14 00:00:00 EDT 2023
Canonical cellular stress granules are required for arsenite-induced necroptosis mediated by Z-DNA-binding protein 1.
Science signaling
Szczerba M,Johnson B,Acciai F,Gogerty C,McCaughan M,Williams J,Kibler KV,Jacobs BL
Tue Mar 14 00:00:00 EDT 2023
Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules.
Autophagy
Yang C,Wang Z,Kang Y,Yi Q,Wang T,Bai Y,Liu Y
Sat Jul 01 00:00:00 EDT 2023
Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules.
Autophagy
Yang C,Wang Z,Kang Y,Yi Q,Wang T,Bai Y,Liu Y
Sat Jul 01 00:00:00 EDT 2023
Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules.
Autophagy
Yang C,Wang Z,Kang Y,Yi Q,Wang T,Bai Y,Liu Y
Sat Jul 01 00:00:00 EDT 2023
Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.
iScience
Miyagi T,Ueda K,Sugimoto M,Yagi T,Ito D,Yamazaki R,Narumi S,Hayamizu Y,Uji-I H,Kuroda M,Kanekura K
Fri Jun 16 00:00:00 EDT 2023
Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspases.
Current biology : CB
Fujikawa D,Nakamura T,Yoshioka D,Li Z,Moriizumi H,Taguchi M,Tokai-Nishizumi N,Kozuka-Hata H,Oyama M,Takekawa M
Mon May 22 00:00:00 EDT 2023
RNA G-quadruplex organizes stress granule assembly through DNAPTP6 in neurons.
Science advances
Asamitsu S,Yabuki Y,Matsuo K,Kawasaki M,Hirose Y,Kashiwazaki G,Chandran A,Bando T,Wang DO,Sugiyama H,Shioda N
Fri Feb 24 00:00:00 EST 2023
Phase-separated nucleocapsid protein of SARS-CoV-2 suppresses cGAS-DNA recognition by disrupting cGAS-G3BP1 complex.
Signal transduction and targeted therapy
Cai S,Zhang C,Zhuang Z,Zhang S,Ma L,Yang S,Zhou T,Wang Z,Xie W,Jin S,Zhao J,Guan X,Wu J,Cui J,Wu Y
Wed Apr 26 00:00:00 EDT 2023
Phase-separated nucleocapsid protein of SARS-CoV-2 suppresses cGAS-DNA recognition by disrupting cGAS-G3BP1 complex.
Signal transduction and targeted therapy
Cai S,Zhang C,Zhuang Z,Zhang S,Ma L,Yang S,Zhou T,Wang Z,Xie W,Jin S,Zhao J,Guan X,Wu J,Cui J,Wu Y
Wed Apr 26 00:00:00 EDT 2023
Genetic Profiling of African American Patients With Prostatic Adenocarcinoma Metastatic to the Lymph Nodes: A Pilot Study.
Archives of pathology & laboratory medicine
Bidot S,Yin J,Zhou P,Zhang L,Deeb KK,Smith G,Hill CE,Xiu J,Bilen MA,Case KB,Tinsley M,Carthon B,Harik LR
Mon Jun 19 00:00:00 EDT 2023
Aggregation-prone TDP-43 sequesters and drives pathological transitions of free nuclear TDP-43.
Cellular and molecular life sciences : CMLS
Keating SS,Bademosi AT,San Gil R,Walker AK
Fri Mar 17 00:00:00 EDT 2023
Stress granule assembly in vivo is deficient in the CNS of mutant TDP-43 ALS mice.
Human molecular genetics
Dubinski A,Gagné M,Peyrard S,Gordon D,Talbot K,Vande Velde C
Fri Jan 06 00:00:00 EST 2023
ZYG11B potentiates the antiviral innate immune response by enhancing cGAS-DNA binding and condensation.
Cell reports
Zhang J,Zhou EC,He Y,Chai ZL,Ji BZ,Tu Y,Wang HL,Wu WQ,Liu Y,Zhang XH,Liu Y
Tue Mar 28 00:00:00 EDT 2023
ZYG11B potentiates the antiviral innate immune response by enhancing cGAS-DNA binding and condensation.
Cell reports
Zhang J,Zhou EC,He Y,Chai ZL,Ji BZ,Tu Y,Wang HL,Wu WQ,Liu Y,Zhang XH,Liu Y
Tue Mar 28 00:00:00 EDT 2023
The ZSWIM8 ubiquitin ligase regulates neurodevelopment by guarding the protein quality of intrinsically disordered Dab1.
Cerebral cortex (New York, N.Y. : 1991)
Wang G,Lei J,Wang Y,Yu J,He Y,Zhao W,Hu Z,Xu Z,Jin Y,Gu Y,Guo X,Yang B,Gao Z,Wang Z
Tue Mar 21 00:00:00 EDT 2023
The ZSWIM8 ubiquitin ligase regulates neurodevelopment by guarding the protein quality of intrinsically disordered Dab1.
Cerebral cortex (New York, N.Y. : 1991)
Wang G,Lei J,Wang Y,Yu J,He Y,Zhao W,Hu Z,Xu Z,Jin Y,Gu Y,Guo X,Yang B,Gao Z,Wang Z
Tue Mar 21 00:00:00 EDT 2023
Screening Linear and Circular RNA Transcripts from Stress Granules.
Genomics, proteomics & bioinformatics
Chen S,Zhang J,Zhao F
Mon Jan 24 00:00:00 EST 2022
Viral evasion of PKR restriction by reprogramming cellular stress granules.
Proceedings of the National Academy of Sciences of the United States of America
Gao P,Liu Y,Wang H,Chai Y,Weng W,Zhang Y,Zhou L,Ge X,Guo X,Han J,Yang H
Tue Jul 19 00:00:00 EDT 2022
Zinc enhances liquid-liquid phase separation of Tau protein and aggravates mitochondrial damages in cells.
International journal of biological macromolecules
Gao YY,Zhong T,Wang LQ,Zhang N,Zeng Y,Hu JY,Dang HB,Chen J,Liang Y
Wed Jun 01 00:00:00 EDT 2022
Zinc enhances liquid-liquid phase separation of Tau protein and aggravates mitochondrial damages in cells.
International journal of biological macromolecules
Gao YY,Zhong T,Wang LQ,Zhang N,Zeng Y,Hu JY,Dang HB,Chen J,Liang Y
Wed Jun 01 00:00:00 EDT 2022
Zinc enhances liquid-liquid phase separation of Tau protein and aggravates mitochondrial damages in cells.
International journal of biological macromolecules
Gao YY,Zhong T,Wang LQ,Zhang N,Zeng Y,Hu JY,Dang HB,Chen J,Liang Y
Wed Jun 01 00:00:00 EDT 2022
Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation.
Molecular cell
Shen H,Yanas A,Owens MC,Zhang C,Fritsch C,Fare CM,Copley KE,Shorter J,Goldman YE,Liu KF
Thu Jul 21 00:00:00 EDT 2022
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.
Signal transduction and targeted therapy
Zheng Y,Deng J,Han L,Zhuang MW,Xu Y,Zhang J,Nan ML,Xiao Y,Zhan P,Liu X,Gao C,Wang PH
Mon Jan 24 00:00:00 EST 2022
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.
Signal transduction and targeted therapy
Zheng Y,Deng J,Han L,Zhuang MW,Xu Y,Zhang J,Nan ML,Xiao Y,Zhan P,Liu X,Gao C,Wang PH
Mon Jan 24 00:00:00 EST 2022
c-Abl Regulates the Pathological Deposition of TDP-43 via Tyrosine 43 Phosphorylation.
Cells
Lee S,Ryu HG,Kweon SH,Kim H,Park H,Lee KH,Jang SM,Na CH,Kim S,Ko HS
Thu Dec 08 00:00:00 EST 2022
LC3B is an RNA-binding protein to trigger rapid mRNA degradation during autophagy.
Nature communications
Hwang HJ,Ha H,Lee BS,Kim BH,Song HK,Kim YK
Thu Mar 17 00:00:00 EDT 2022
Proximity-based labeling reveals DNA damage-induced phosphorylation of fused in sarcoma (FUS) causes distinct changes in the FUS protein interactome.
The Journal of biological chemistry
Johnson MA,Nuckols TA,Merino P,Bagchi P,Nandy S,Root J,Taylor G,Seyfried NT,Kukar T
Mon Aug 01 00:00:00 EDT 2022
Proximity-based labeling reveals DNA damage-induced phosphorylation of fused in sarcoma (FUS) causes distinct changes in the FUS protein interactome.
The Journal of biological chemistry
Johnson MA,Nuckols TA,Merino P,Bagchi P,Nandy S,Root J,Taylor G,Seyfried NT,Kukar T
Mon Aug 01 00:00:00 EDT 2022
The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm.
Non-coding RNA
Kirchhof L,Fouani Y,Knau A,Aslan GS,Heumüller AW,Wittig I,Müller-McNicoll M,Dimmeler S,Jaé N
Thu Jun 30 00:00:00 EDT 2022
The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm.
Non-coding RNA
Kirchhof L,Fouani Y,Knau A,Aslan GS,Heumüller AW,Wittig I,Müller-McNicoll M,Dimmeler S,Jaé N
Thu Jun 30 00:00:00 EDT 2022
The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm.
Non-coding RNA
Kirchhof L,Fouani Y,Knau A,Aslan GS,Heumüller AW,Wittig I,Müller-McNicoll M,Dimmeler S,Jaé N
Thu Jun 30 00:00:00 EDT 2022
RNA supply drives physiological granule assembly in neurons.
Nature communications
Bauer KE,Bargenda N,Schieweck R,Illig C,Segura I,Harner M,Kiebler MA
Thu May 19 00:00:00 EDT 2022
MxB inhibits long interspersed element type 1 retrotransposition.
PLoS genetics
Huang Y,Xu F,Mei S,Liu X,Zhao F,Wei L,Fan Z,Hu Y,Wang L,Ai B,Cen S,Liang C,Guo F
Tue Feb 01 00:00:00 EST 2022
MxB inhibits long interspersed element type 1 retrotransposition.
PLoS genetics
Huang Y,Xu F,Mei S,Liu X,Zhao F,Wei L,Fan Z,Hu Y,Wang L,Ai B,Cen S,Liang C,Guo F
Tue Feb 01 00:00:00 EST 2022
CircEIF3H-IGF2BP2-HuR scaffold complex promotes TNBC progression via stabilizing HSPD1/RBM8A/G3BP1 mRNA.
Cell death discovery
Song X,Chen B,Liang Y,Li Y,Zhang H,Han D,Wang Y,Ye F,Wang L,Zhao W,Yang Q
Sat May 14 00:00:00 EDT 2022
Tumor-promoting properties of karyopherin β1 in melanoma by stabilizing Ras-GTPase-activating protein SH3 domain-binding protein 1.
Cancer gene therapy
Yang F,Li L,Mu Z,Liu P,Wang Y,Zhang Y,Han X
Thu Dec 01 00:00:00 EST 2022
Impaired Restoration of Global Protein Synthesis Contributes to Increased Vulnerability to Acute ER Stress Recovery in Huntington's Disease.
Cellular and molecular neurobiology
Xu H,Bensalel J,Capobianco E,Lu ML,Wei J
Tue Nov 01 00:00:00 EDT 2022
ALS-linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain-of-function.
EMBO reports
Pant DC,Parameswaran J,Rao L,Loss I,Chilukuri G,Parlato R,Shi L,Glass JD,Bassell GJ,Koch P,Yilmaz R,Weishaupt JH,Gennerich A,Jiang J
Wed Aug 03 00:00:00 EDT 2022
Nuclear RNA transcript levels modulate nucleocytoplasmic distribution of ALS/FTD-associated protein FUS.
Scientific reports
Tsai YL,Mu YC,Manley JL
Tue May 17 00:00:00 EDT 2022
cGAS inhibition alleviates Alu RNA-induced immune responses and cytotoxicity in retinal pigmented epithelium.
Cell & bioscience
Li J,Zhang F,Bian W,Chen Y,Liu J,Liu Z,Xiong Y,Wan X
Mon Jul 25 00:00:00 EDT 2022
Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.
The EMBO journal
Gruijs da Silva LA,Simonetti F,Hutten S,Riemenschneider H,Sternburg EL,Pietrek LM,Gebel J,Dötsch V,Edbauer D,Hummer G,Stelzl LS,Dormann D
Tue Apr 19 00:00:00 EDT 2022
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Translational stroke research
Lu D,Liu Y,Huang H,Hu M,Li T,Wang S,Shen S,Wu R,Cai W,Lu T,Lu Z
Sat Oct 01 00:00:00 EDT 2022
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Translational stroke research
Lu D,Liu Y,Huang H,Hu M,Li T,Wang S,Shen S,Wu R,Cai W,Lu T,Lu Z
Sat Oct 01 00:00:00 EDT 2022
Upregulated LINC01088 facilitates malignant phenotypes and immune escape of colorectal cancer by regulating microRNAs/G3BP1/PD-L1 axis.
Journal of cancer research and clinical oncology
Li C,Pan B,Wang X,Liu X,Qin J,Gao T,Sun H,Pan Y,Wang S
Mon Aug 01 00:00:00 EDT 2022
C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α.
Theranostics
Zheng W,Wang K,Wu Y,Yan G,Zhang C,Li Z,Wang L,Chen S
Thu Dec 08 00:00:00 EST 2022
ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids.
Cell
Bowles KR,Silva MC,Whitney K,Bertucci T,Berlind JE,Lai JD,Garza JC,Boles NC,Mahali S,Strang KH,Marsh JA,Chen C,Pugh DA,Liu Y,Gordon RE,Goderie SK,Chowdhury R,Lotz S,Lane K,Crary JF,Haggarty SJ,Karch CM,Ichida JK,Goate AM,Temple S
Thu Aug 19 00:00:00 EDT 2021
Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner.
Science (New York, N.Y.)
Gwon Y,Maxwell BA,Kolaitis RM,Zhang P,Kim HJ,Taylor JP
Fri Jun 25 00:00:00 EDT 2021
Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner.
Science (New York, N.Y.)
Gwon Y,Maxwell BA,Kolaitis RM,Zhang P,Kim HJ,Taylor JP
Fri Jun 25 00:00:00 EDT 2021
FUS/TLS Suppresses Enterovirus Replication and Promotes Antiviral Innate Immune Responses.
Journal of virology
Xue YC,Ng CS,Mohamud Y,Fung G,Liu H,Bahreyni A,Zhang J,Luo H
Mon May 24 00:00:00 EDT 2021
ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD.
Nucleic acids research
Park J,Lee J,Kim JH,Lee J,Park H,Lim C
Mon Nov 08 00:00:00 EST 2021
Interactome analysis illustrates diverse gene regulatory processes associated with LIN28A in human iPS cell-derived neural progenitor cells.
iScience
Yu NK,McClatchy DB,Diedrich JK,Romero S,Choi JH,Martínez-Bartolomé S,Delahunty CM,Muotri AR,Yates JR
Fri Nov 19 00:00:00 EST 2021
TDP-43 stabilizes G3BP1 mRNA: relevance to amyotrophic lateral sclerosis/frontotemporal dementia.
Brain : a journal of neurology
Sidibé H,Khalfallah Y,Xiao S,Gómez NB,Fakim H,Tank EMH,Di Tomasso G,Bareke E,Aulas A,McKeever PM,Melamed Z,Destroimaisons L,Deshaies JE,Zinman L,Parker JA,Legault P,Tétreault M,Barmada SJ,Robertson J,Vande Velde C
Thu Dec 16 00:00:00 EST 2021
The pioneer round of translation ensures proper targeting of ER and mitochondrial proteins.
Nucleic acids research
Park J,Chang J,Hwang HJ,Jeong K,Lee HJ,Ha H,Park Y,Lim C,Woo JS,Kim YK
Thu Dec 02 00:00:00 EST 2021
c-Myc-activated USP2-AS1 suppresses senescence and promotes tumor progression via stabilization of E2F1 mRNA.
Cell death & disease
Li B,Zhang G,Wang Z,Yang Y,Wang C,Fang D,Liu K,Wang F,Mei Y
Wed Oct 27 00:00:00 EDT 2021
c-Myc-activated USP2-AS1 suppresses senescence and promotes tumor progression via stabilization of E2F1 mRNA.
Cell death & disease
Li B,Zhang G,Wang Z,Yang Y,Wang C,Fang D,Liu K,Wang F,Mei Y
Wed Oct 27 00:00:00 EDT 2021
Inhibition of eIF2α Phosphorylation by Peste des Petits Ruminant Virus Phosphoprotein Facilitates Viral Replication.
Frontiers in veterinary science
Alfred N,Qian B,Qin X,Yin X,Prajapati M,Dou Y,Li Y,Zhang Z
Sat Jul 24 00:00:00 EDT 2021
TLR and IKK Complex-Mediated Innate Immune Signaling Inhibits Stress Granule Assembly.
Journal of immunology (Baltimore, Md. : 1950)
Samir P,Place DE,Malireddi RKS,Kanneganti TD
Thu Jul 01 00:00:00 EDT 2021
TLR and IKK Complex-Mediated Innate Immune Signaling Inhibits Stress Granule Assembly.
Journal of immunology (Baltimore, Md. : 1950)
Samir P,Place DE,Malireddi RKS,Kanneganti TD
Thu Jul 01 00:00:00 EDT 2021
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
Nature structural & molecular biology
Zuo X,Zhou J,Li Y,Wu K,Chen Z,Luo Z,Zhang X,Liang Y,Esteban MA,Zhou Y,Fu XD
Mon Feb 01 00:00:00 EST 2021
Phosphorylation Regulates CIRBP Arginine Methylation, Transportin-1 Binding and Liquid-Liquid Phase Separation.
Frontiers in molecular biosciences
Lenard AJ,Hutten S,Zhou Q,Usluer S,Zhang F,Bourgeois BMR,Dormann D,Madl T
Wed Aug 03 00:00:00 EDT 2022
DDX17 is involved in DNA damage repair and modifies FUS toxicity in an RGG-domain dependent manner.
Acta neuropathologica
Fortuna TR,Kour S,Anderson EN,Ward C,Rajasundaram D,Donnelly CJ,Hermann A,Wyne H,Shewmaker F,Pandey UB
Wed Sep 01 00:00:00 EDT 2021
Myricetin slows liquid-liquid phase separation of Tau and activates ATG5-dependent autophagy to suppress Tau toxicity.
The Journal of biological chemistry
Dai B,Zhong T,Chen ZX,Chen W,Zhang N,Liu XL,Wang LQ,Chen J,Liang Y
Fri Oct 01 00:00:00 EDT 2021
Proteomic analysis identifies the RNA helicase DDX3X as a host target against SARS-CoV-2 infection.
Antiviral research
Ciccosanti F,Di Rienzo M,Romagnoli A,Colavita F,Refolo G,Castilletti C,Agrati C,Brai A,Manetti F,Botta L,Capobianchi MR,Ippolito G,Piacentini M,Fimia GM
Tue Jun 01 00:00:00 EDT 2021
Proteomic analysis identifies the RNA helicase DDX3X as a host target against SARS-CoV-2 infection.
Antiviral research
Ciccosanti F,Di Rienzo M,Romagnoli A,Colavita F,Refolo G,Castilletti C,Agrati C,Brai A,Manetti F,Botta L,Capobianchi MR,Ippolito G,Piacentini M,Fimia GM
Tue Jun 01 00:00:00 EDT 2021
The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors.
The Journal of biological chemistry
Baade I,Hutten S,Sternburg EL,Pörschke M,Hofweber M,Dormann D,Kehlenbach RH
Mon Aug 23 00:00:00 EDT 2021
Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function.
Diabetologia
Zhang M,Yang C,Zhu M,Qian L,Luo Y,Cheng H,Geng R,Xu X,Qian C,Liu Y
Sat May 01 00:00:00 EDT 2021
Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function.
Diabetologia
Zhang M,Yang C,Zhu M,Qian L,Luo Y,Cheng H,Geng R,Xu X,Qian C,Liu Y
Sat May 01 00:00:00 EDT 2021
Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function.
Diabetologia
Zhang M,Yang C,Zhu M,Qian L,Luo Y,Cheng H,Geng R,Xu X,Qian C,Liu Y
Sat May 01 00:00:00 EDT 2021
Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function.
Diabetologia
Zhang M,Yang C,Zhu M,Qian L,Luo Y,Cheng H,Geng R,Xu X,Qian C,Liu Y
Sat May 01 00:00:00 EDT 2021
Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function.
Diabetologia
Zhang M,Yang C,Zhu M,Qian L,Luo Y,Cheng H,Geng R,Xu X,Qian C,Liu Y
Sat May 01 00:00:00 EDT 2021
Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function.
Diabetologia
Zhang M,Yang C,Zhu M,Qian L,Luo Y,Cheng H,Geng R,Xu X,Qian C,Liu Y
Sat May 01 00:00:00 EDT 2021
DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response.
The Journal of biological chemistry
Kesavardhana S,Samir P,Zheng M,Malireddi RKS,Karki R,Sharma BR,Place DE,Briard B,Vogel P,Kanneganti TD
Wed Aug 18 00:00:00 EDT 2021
DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response.
The Journal of biological chemistry
Kesavardhana S,Samir P,Zheng M,Malireddi RKS,Karki R,Sharma BR,Place DE,Briard B,Vogel P,Kanneganti TD
Wed Aug 18 00:00:00 EDT 2021
SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production.
Science bulletin
Luo L,Li Z,Zhao T,Ju X,Ma P,Jin B,Zhou Y,He S,Huang J,Xu X,Zou Y,Li P,Liang A,Liu J,Chi T,Huang X,Ding Q,Jin Z,Huang C,Zhang Y
Wed Jun 30 00:00:00 EDT 2021
LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient.
PLoS biology
Lee J,Park J,Kim JH,Lee G,Park TE,Yoon KJ,Kim YK,Lim C
Tue Dec 01 00:00:00 EST 2020
Missing in Action: Dysfunctional RNA Metabolism in Oligodendroglial Cells as a Contributor to Neurodegenerative Diseases?
Neurochemical research
Hoch-Kraft P,Trotter J,Gonsior C
Sun Mar 01 00:00:00 EST 2020
ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs.
Genes & development
Tsai YL,Coady TH,Lu L,Zheng D,Alland I,Tian B,Shneider NA,Manley JL
Mon Jun 01 00:00:00 EDT 2020
HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection.
Frontiers in microbiology
Zheng Y,Zhu G,Tang Y,Yan J,Han S,Yin J,Peng B,He X,Liu W
Mon Sep 28 00:00:00 EDT 2020
HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection.
Frontiers in microbiology
Zheng Y,Zhu G,Tang Y,Yan J,Han S,Yin J,Peng B,He X,Liu W
Mon Sep 28 00:00:00 EDT 2020
Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism.
iScience
Valdez-Sinon AN,Lai A,Shi L,Lancaster CL,Gokhale A,Faundez V,Bassell GJ
Fri May 22 00:00:00 EDT 2020
Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism.
iScience
Valdez-Sinon AN,Lai A,Shi L,Lancaster CL,Gokhale A,Faundez V,Bassell GJ
Fri May 22 00:00:00 EDT 2020
Capturing RNA-protein interaction via CRUIS.
Nucleic acids research
Zhang Z,Sun W,Shi T,Lu P,Zhuang M,Liu JL
Thu May 21 00:00:00 EDT 2020
Typical Stress Granule Proteins Interact with the 3' Untranslated Region of Enterovirus D68 To Inhibit Viral Replication.
Journal of virology
Cheng J,Gao S,Zhu C,Liu S,Li J,Kang J,Wang Z,Wang T
Tue Mar 17 00:00:00 EDT 2020
Typical Stress Granule Proteins Interact with the 3' Untranslated Region of Enterovirus D68 To Inhibit Viral Replication.
Journal of virology
Cheng J,Gao S,Zhu C,Liu S,Li J,Kang J,Wang Z,Wang T
Tue Mar 17 00:00:00 EDT 2020
The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation.
Cell reports
Lo LH,Dong R,Lyu Q,Lai KO
Tue Jun 09 00:00:00 EDT 2020
The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation.
Cell reports
Lo LH,Dong R,Lyu Q,Lai KO
Tue Jun 09 00:00:00 EDT 2020
Rapid prediction of drug inhibition under heat stress: single-photon imaging combined with a convolutional neural network.
Nanoscale
Lin H,Xie J,Fan T,He Y,Chen J,Zhang H,Zhuo S
Thu Nov 26 00:00:00 EST 2020
Lysine acetylation regulates the RNA binding, subcellular localization and inclusion formation of FUS.
Human molecular genetics
Arenas A,Chen J,Kuang L,Barnett KR,Kasarskis EJ,Gal J,Zhu H
Tue Sep 29 00:00:00 EDT 2020
A Quantitative Assay to Measure Stress Granule Association of Proteins and Peptidesin Semi-permeabilized Human Cells.
Bio-protocol
Hutten S,Dormann D
Sun Dec 20 00:00:00 EST 2020
ALS-Linked Mutant SOD1 Associates with TIA-1 and Alters Stress Granule Dynamics.
Neurochemical research
Lee DY,Jeon GS,Sung JJ
Tue Dec 01 00:00:00 EST 2020
ALS-Linked Mutant SOD1 Associates with TIA-1 and Alters Stress Granule Dynamics.
Neurochemical research
Lee DY,Jeon GS,Sung JJ
Tue Dec 01 00:00:00 EST 2020
Post-Transcriptional Regulation of Alpha One Antitrypsin by a Proteasome Inhibitor.
International journal of molecular sciences
Rao L,Xu Y,Reineke LC,Bhattacharya A,Tyryshkin A,Shin JN,Eissa NT
Wed Jun 17 00:00:00 EDT 2020
Diagnostic and prognostic values of PBMC proteins in amyotrophic lateral sclerosis.
Neurobiology of disease
Luotti S,Pasetto L,Porcu L,Torri V,Elezgarai SR,Pantalone S,Filareti M,Corbo M,Lunetta C,Mora G,Bonetto V
Mon Jun 01 00:00:00 EDT 2020
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Journal of virology
Zheng Y,Zhu G,Yan J,Tang Y,Han S,Yin J,Peng B,He X,Liu W
Tue Mar 17 00:00:00 EDT 2020
Endoplasmic Reticulum Stress Signalling Induces Casein Kinase 1-Dependent Formation of Cytosolic TDP-43 Inclusions in Motor Neuron-Like Cells.
Neurochemical research
Hicks DA,Cross LL,Williamson R,Rattray M
Mon Jun 01 00:00:00 EDT 2020
Endoplasmic Reticulum Stress Signalling Induces Casein Kinase 1-Dependent Formation of Cytosolic TDP-43 Inclusions in Motor Neuron-Like Cells.
Neurochemical research
Hicks DA,Cross LL,Williamson R,Rattray M
Mon Jun 01 00:00:00 EDT 2020
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether.
Cell
Liao YC,Fernandopulle MS,Wang G,Choi H,Hao L,Drerup CM,Patel R,Qamar S,Nixon-Abell J,Shen Y,Meadows W,Vendruscolo M,Knowles TPJ,Nelson M,Czekalska MA,Musteikyte G,Gachechiladze MA,Stephens CA,Pasolli HA,Forrest LR,St George-Hyslop P,Lippincott-Schwartz J,Ward ME
Thu Sep 19 00:00:00 EDT 2019
G3BP1 promotes DNA binding and activation of cGAS.
Nature immunology
Liu ZS,Cai H,Xue W,Wang M,Xia T,Li WJ,Xing JQ,Zhao M,Huang YJ,Chen S,Wu SM,Wang X,Liu X,Pang X,Zhang ZY,Li T,Dai J,Dong F,Xia Q,Li AL,Zhou T,Liu ZG,Zhang XM,Li T
Tue Jan 01 00:00:00 EST 2019
G3BP1 promotes DNA binding and activation of cGAS.
Nature immunology
Liu ZS,Cai H,Xue W,Wang M,Xia T,Li WJ,Xing JQ,Zhao M,Huang YJ,Chen S,Wu SM,Wang X,Liu X,Pang X,Zhang ZY,Li T,Dai J,Dong F,Xia Q,Li AL,Zhou T,Liu ZG,Zhang XM,Li T
Tue Jan 01 00:00:00 EST 2019
ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.
Molecular cell
Wang B,Maxwell BA,Joo JH,Gwon Y,Messing J,Mishra A,Shaw TI,Ward AL,Quan H,Sakurada SM,Pruett-Miller SM,Bertorini T,Vogel P,Kim HJ,Peng J,Taylor JP,Kundu M
Thu May 16 00:00:00 EDT 2019
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.
Neuron
Mann JR,Gleixner AM,Mauna JC,Gomes E,DeChellis-Marks MR,Needham PG,Copley KE,Hurtle B,Portz B,Pyles NJ,Guo L,Calder CB,Wills ZP,Pandey UB,Kofler JK,Brodsky JL,Thathiah A,Shorter J,Donnelly CJ
Wed Apr 17 00:00:00 EDT 2019
Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology.
Cell death and differentiation
Silva JM,Rodrigues S,Sampaio-Marques B,Gomes P,Neves-Carvalho A,Dioli C,Soares-Cunha C,Mazuik BF,Takashima A,Ludovico P,Wolozin B,Sousa N,Sotiropoulos I
Thu Aug 01 00:00:00 EDT 2019
Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology.
Cell death and differentiation
Silva JM,Rodrigues S,Sampaio-Marques B,Gomes P,Neves-Carvalho A,Dioli C,Soares-Cunha C,Mazuik BF,Takashima A,Ludovico P,Wolozin B,Sousa N,Sotiropoulos I
Thu Aug 01 00:00:00 EDT 2019
Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology.
Cell death and differentiation
Silva JM,Rodrigues S,Sampaio-Marques B,Gomes P,Neves-Carvalho A,Dioli C,Soares-Cunha C,Mazuik BF,Takashima A,Ludovico P,Wolozin B,Sousa N,Sotiropoulos I
Thu Aug 01 00:00:00 EDT 2019
Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology.
Cell death and differentiation
Silva JM,Rodrigues S,Sampaio-Marques B,Gomes P,Neves-Carvalho A,Dioli C,Soares-Cunha C,Mazuik BF,Takashima A,Ludovico P,Wolozin B,Sousa N,Sotiropoulos I
Thu Aug 01 00:00:00 EDT 2019
STAU1 binds to IBDV genomic double-stranded RNA and promotes viral replication via attenuation of MDA5-dependent β interferon induction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ye C,Yu Z,Xiong Y,Wang Y,Ruan Y,Guo Y,Chen M,Luan S,Zhang E,Liu H
Tue Jan 01 00:00:00 EST 2019
STAU1 binds to IBDV genomic double-stranded RNA and promotes viral replication via attenuation of MDA5-dependent β interferon induction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ye C,Yu Z,Xiong Y,Wang Y,Ruan Y,Guo Y,Chen M,Luan S,Zhang E,Liu H
Tue Jan 01 00:00:00 EST 2019
Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS.
Human molecular genetics
Baron DM,Matheny T,Lin YC,Leszyk JD,Kenna K,Gall KV,Santos DP,Tischbein M,Funes S,Hayward LJ,Kiskinis E,Landers JE,Parker R,Shaffer SA,Bosco DA
Mon Jul 01 00:00:00 EDT 2019
The Acetylation of Lysine-376 of G3BP1 Regulates RNA Binding and Stress Granule Dynamics.
Molecular and cellular biology
Gal J,Chen J,Na DY,Tichacek L,Barnett KR,Zhu H
Fri Nov 15 00:00:00 EST 2019
The Acetylation of Lysine-376 of G3BP1 Regulates RNA Binding and Stress Granule Dynamics.
Molecular and cellular biology
Gal J,Chen J,Na DY,Tichacek L,Barnett KR,Zhu H
Fri Nov 15 00:00:00 EST 2019
Lysine/RNA-interactions drive and regulate biomolecular condensation.
Nature communications
Ukmar-Godec T,Hutten S,Grieshop MP,Rezaei-Ghaleh N,Cima-Omori MS,Biernat J,Mandelkow E,Söding J,Dormann D,Zweckstetter M
Tue Jul 02 00:00:00 EDT 2019
PKR-dependent cytosolic cGAS foci are necessary for intracellular DNA sensing.
Science signaling
Hu S,Sun H,Yin L,Li J,Mei S,Xu F,Wu C,Liu X,Zhao F,Zhang D,Huang Y,Ren L,Cen S,Wang J,Liang C,Guo F
Tue Nov 26 00:00:00 EST 2019
PKR-dependent cytosolic cGAS foci are necessary for intracellular DNA sensing.
Science signaling
Hu S,Sun H,Yin L,Li J,Mei S,Xu F,Wu C,Liu X,Zhao F,Zhang D,Huang Y,Ren L,Cen S,Wang J,Liang C,Guo F
Tue Nov 26 00:00:00 EST 2019
Stress granules are formed in renal proximal tubular cells during metabolic stress and ischemic injury for cell survival.
American journal of physiology. Renal physiology
Wang S,Kwon SH,Su Y,Dong Z
Mon Jul 01 00:00:00 EDT 2019
G3BP1 activates the TGF-β/Smad signaling pathway to promote gastric cancer.
OncoTargets and therapy
Xiong R,Gao JL,Yin T
Sun Apr 10 00:00:00 EDT 2022
Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells.
Cell reports
Franchini DM,Lanvin O,Tosolini M,Patras de Campaigno E,Cammas A,Péricart S,Scarlata CM,Lebras M,Rossi C,Ligat L,Pont F,Arimondo PB,Laurent C,Ayyoub M,Despas F,Lapeyre-Mestre M,Millevoi S,Fournié JJ
Wed Jan 02 00:00:00 EST 2019
Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells.
Cell reports
Franchini DM,Lanvin O,Tosolini M,Patras de Campaigno E,Cammas A,Péricart S,Scarlata CM,Lebras M,Rossi C,Ligat L,Pont F,Arimondo PB,Laurent C,Ayyoub M,Despas F,Lapeyre-Mestre M,Millevoi S,Fournié JJ
Wed Jan 02 00:00:00 EST 2019
The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for GRIA2 mRNA processing.
The Journal of biological chemistry
Tischbein M,Baron DM,Lin YC,Gall KV,Landers JE,Fallini C,Bosco DA
Fri Jun 28 00:00:00 EDT 2019
Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression.
Nature cell biology
Cai D,Feliciano D,Dong P,Flores E,Gruebele M,Porat-Shliom N,Sukenik S,Liu Z,Lippincott-Schwartz J
Sun Dec 01 00:00:00 EST 2019
m6A enhances the phase separation potential of mRNA.
Nature
Ries RJ,Zaccara S,Klein P,Olarerin-George A,Namkoong S,Pickering BF,Patil DP,Kwak H,Lee JH,Jaffrey SR
Mon Jul 01 00:00:00 EDT 2019
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Cell
Hofweber M,Hutten S,Bourgeois B,Spreitzer E,Niedner-Boblenz A,Schifferer M,Ruepp MD,Simons M,Niessing D,Madl T,Dormann D
Thu Apr 19 00:00:00 EDT 2018
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Cell
Hofweber M,Hutten S,Bourgeois B,Spreitzer E,Niedner-Boblenz A,Schifferer M,Ruepp MD,Simons M,Niessing D,Madl T,Dormann D
Thu Apr 19 00:00:00 EDT 2018
TIA1 variant drives myodegeneration in multisystem proteinopathy with SQSTM1 mutations.
The Journal of clinical investigation
Lee Y,Jonson PH,Sarparanta J,Palmio J,Sarkar M,Vihola A,Evilä A,Suominen T,Penttilä S,Savarese M,Johari M,Minot MC,Hilton-Jones D,Maddison P,Chinnery P,Reimann J,Kornblum C,Kraya T,Zierz S,Sue C,Goebel H,Azfer A,Ralston SH,Hackman P,Bucelli RC,Taylor JP,Weihl CC,Udd B
Thu Mar 01 00:00:00 EST 2018
TIA1 variant drives myodegeneration in multisystem proteinopathy with SQSTM1 mutations.
The Journal of clinical investigation
Lee Y,Jonson PH,Sarparanta J,Palmio J,Sarkar M,Vihola A,Evilä A,Suominen T,Penttilä S,Savarese M,Johari M,Minot MC,Hilton-Jones D,Maddison P,Chinnery P,Reimann J,Kornblum C,Kraya T,Zierz S,Sue C,Goebel H,Azfer A,Ralston SH,Hackman P,Bucelli RC,Taylor JP,Weihl CC,Udd B
Thu Mar 01 00:00:00 EST 2018
High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.
Molecular cell
Youn JY,Dunham WH,Hong SJ,Knight JDR,Bashkurov M,Chen GI,Bagci H,Rathod B,MacLeod G,Eng SWM,Angers S,Morris Q,Fabian M,Côté JF,Gingras AC
Thu Feb 01 00:00:00 EST 2018
High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.
Molecular cell
Youn JY,Dunham WH,Hong SJ,Knight JDR,Bashkurov M,Chen GI,Bagci H,Rathod B,MacLeod G,Eng SWM,Angers S,Morris Q,Fabian M,Côté JF,Gingras AC
Thu Feb 01 00:00:00 EST 2018
O-GlcNAc modification of eIF4GI acts as a translational switch in heat shock response.
Nature chemical biology
Zhang X,Shu XE,Qian SB
Mon Oct 01 00:00:00 EDT 2018
O-GlcNAc modification of eIF4GI acts as a translational switch in heat shock response.
Nature chemical biology
Zhang X,Shu XE,Qian SB
Mon Oct 01 00:00:00 EDT 2018
Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS.
Journal of virology
Burgess HM,Mohr I
Wed Aug 01 00:00:00 EDT 2018
Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS.
Journal of virology
Burgess HM,Mohr I
Wed Aug 01 00:00:00 EDT 2018
Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS.
Journal of virology
Burgess HM,Mohr I
Wed Aug 01 00:00:00 EDT 2018
Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS.
Journal of virology
Burgess HM,Mohr I
Wed Aug 01 00:00:00 EDT 2018
The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation.
Mobile DNA
Herrmann A,Wittmann S,Thomas D,Shepard CN,Kim B,Ferreirós N,Gramberg T
Wed Mar 16 00:00:00 EDT 2022
The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation.
Mobile DNA
Herrmann A,Wittmann S,Thomas D,Shepard CN,Kim B,Ferreirós N,Gramberg T
Wed Mar 16 00:00:00 EDT 2022
Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1.
Scientific reports
Ederle H,Funk C,Abou-Ajram C,Hutten S,Funk EBE,Kehlenbach RH,Bailer SM,Dormann D
Fri May 04 00:00:00 EDT 2018
Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1.
Scientific reports
Ederle H,Funk C,Abou-Ajram C,Hutten S,Funk EBE,Kehlenbach RH,Bailer SM,Dormann D
Fri May 04 00:00:00 EDT 2018
A GTPase-activating protein-binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells.
The Journal of biological chemistry
Ramachandran B,Stabley JN,Cheng SL,Behrmann AS,Gay A,Li L,Mead M,Kozlitina J,Lemoff A,Mirzaei H,Chen Z,Towler DA
Fri May 25 00:00:00 EDT 2018
A GTPase-activating protein-binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells.
The Journal of biological chemistry
Ramachandran B,Stabley JN,Cheng SL,Behrmann AS,Gay A,Li L,Mead M,Kozlitina J,Lemoff A,Mirzaei H,Chen Z,Towler DA
Fri May 25 00:00:00 EDT 2018
A GTPase-activating protein-binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells.
The Journal of biological chemistry
Ramachandran B,Stabley JN,Cheng SL,Behrmann AS,Gay A,Li L,Mead M,Kozlitina J,Lemoff A,Mirzaei H,Chen Z,Towler DA
Fri May 25 00:00:00 EDT 2018
Arsenite-induced stress granule formation is inhibited by elevated levels of reduced glutathione in West Nile virus-infected cells.
PLoS pathogens
Basu M,Courtney SC,Brinton MA
Wed Feb 01 00:00:00 EST 2017
Arsenite-induced stress granule formation is inhibited by elevated levels of reduced glutathione in West Nile virus-infected cells.
PLoS pathogens
Basu M,Courtney SC,Brinton MA
Wed Feb 01 00:00:00 EST 2017
Human Metapneumovirus Induces Formation of Inclusion Bodies for Efficient Genome Replication and Transcription.
Journal of virology
Cifuentes-Muñoz N,Branttie J,Slaughter KB,Dutch RE
Fri Dec 15 00:00:00 EST 2017
Human Metapneumovirus Induces Formation of Inclusion Bodies for Efficient Genome Replication and Transcription.
Journal of virology
Cifuentes-Muñoz N,Branttie J,Slaughter KB,Dutch RE
Fri Dec 15 00:00:00 EST 2017
Casein Kinase 2 Is Linked to Stress Granule Dynamics through Phosphorylation of the Stress Granule Nucleating Protein G3BP1.
Molecular and cellular biology
Reineke LC,Tsai WC,Jain A,Kaelber JT,Jung SY,Lloyd RE
Wed Feb 15 00:00:00 EST 2017
Casein Kinase 2 Is Linked to Stress Granule Dynamics through Phosphorylation of the Stress Granule Nucleating Protein G3BP1.
Molecular and cellular biology
Reineke LC,Tsai WC,Jain A,Kaelber JT,Jung SY,Lloyd RE
Wed Feb 15 00:00:00 EST 2017
Clinical and experimental studies of a novel P525R FUS mutation in amyotrophic lateral sclerosis.
Neurology. Genetics
Kuang L,Kamelgarn M,Arenas A,Gal J,Taylor D,Gong W,Brown M,St Clair D,Kasarskis EJ,Zhu H
Tue Aug 01 00:00:00 EDT 2017
Clinical and experimental studies of a novel P525R FUS mutation in amyotrophic lateral sclerosis.
Neurology. Genetics
Kuang L,Kamelgarn M,Arenas A,Gal J,Taylor D,Gong W,Brown M,St Clair D,Kasarskis EJ,Zhu H
Tue Aug 01 00:00:00 EDT 2017
De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies.
Scientific reports
Mitsuhashi K,Ito D,Mashima K,Oyama M,Takahashi S,Suzuki N
Mon Dec 04 00:00:00 EST 2017
De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies.
Scientific reports
Mitsuhashi K,Ito D,Mashima K,Oyama M,Takahashi S,Suzuki N
Mon Dec 04 00:00:00 EST 2017
ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics.
Acta neuropathologica
Gal J,Kuang L,Barnett KR,Zhu BZ,Shissler SC,Korotkov KV,Hayward LJ,Kasarskis EJ,Zhu H
Sat Oct 01 00:00:00 EDT 2016
ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics.
Acta neuropathologica
Gal J,Kuang L,Barnett KR,Zhu BZ,Shissler SC,Korotkov KV,Hayward LJ,Kasarskis EJ,Zhu H
Sat Oct 01 00:00:00 EDT 2016
ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics.
Acta neuropathologica
Gal J,Kuang L,Barnett KR,Zhu BZ,Shissler SC,Korotkov KV,Hayward LJ,Kasarskis EJ,Zhu H
Sat Oct 01 00:00:00 EDT 2016
ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics.
Acta neuropathologica
Gal J,Kuang L,Barnett KR,Zhu BZ,Shissler SC,Korotkov KV,Hayward LJ,Kasarskis EJ,Zhu H
Sat Oct 01 00:00:00 EDT 2016
Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.
Acta neuropathologica
Daigle JG,Krishnamurthy K,Ramesh N,Casci I,Monaghan J,McAvoy K,Godfrey EW,Daniel DC,Johnson EM,Monahan Z,Shewmaker F,Pasinelli P,Pandey UB
Fri Apr 01 00:00:00 EDT 2016
Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.
Acta neuropathologica
Daigle JG,Krishnamurthy K,Ramesh N,Casci I,Monaghan J,McAvoy K,Godfrey EW,Daniel DC,Johnson EM,Monahan Z,Shewmaker F,Pasinelli P,Pandey UB
Fri Apr 01 00:00:00 EDT 2016
Mislocated FUS is sufficient for gain-of-toxic-function amyotrophic lateral sclerosis phenotypes in mice.
Brain : a journal of neurology
Shiihashi G,Ito D,Yagi T,Nihei Y,Ebine T,Suzuki N
Thu Sep 01 00:00:00 EDT 2016
Mislocated FUS is sufficient for gain-of-toxic-function amyotrophic lateral sclerosis phenotypes in mice.
Brain : a journal of neurology
Shiihashi G,Ito D,Yagi T,Nihei Y,Ebine T,Suzuki N
Thu Sep 01 00:00:00 EDT 2016
The Myoblast C2C12 Transfected with Mutant Valosin-Containing Protein Exhibits Delayed Stress Granule Resolution on Oxidative Stress.
The American journal of pathology
Rodriguez-Ortiz CJ,Flores JC,Valenzuela JA,Rodriguez GJ,Zumkehr J,Tran DN,Kimonis VE,Kitazawa M
Wed Jun 01 00:00:00 EDT 2016
The Myoblast C2C12 Transfected with Mutant Valosin-Containing Protein Exhibits Delayed Stress Granule Resolution on Oxidative Stress.
The American journal of pathology
Rodriguez-Ortiz CJ,Flores JC,Valenzuela JA,Rodriguez GJ,Zumkehr J,Tran DN,Kimonis VE,Kitazawa M
Wed Jun 01 00:00:00 EDT 2016
The Myoblast C2C12 Transfected with Mutant Valosin-Containing Protein Exhibits Delayed Stress Granule Resolution on Oxidative Stress.
The American journal of pathology
Rodriguez-Ortiz CJ,Flores JC,Valenzuela JA,Rodriguez GJ,Zumkehr J,Tran DN,Kimonis VE,Kitazawa M
Wed Jun 01 00:00:00 EDT 2016
Folliculin, a tumor suppressor associated with Birt-Hogg-Dubé (BHD) syndrome, is a novel modifier of TDP-43 cytoplasmic translocation and aggregation.
Human molecular genetics
Xia Q,Wang G,Wang H,Hu Q,Ying Z
Fri Jan 01 00:00:00 EST 2016
Folliculin, a tumor suppressor associated with Birt-Hogg-Dubé (BHD) syndrome, is a novel modifier of TDP-43 cytoplasmic translocation and aggregation.
Human molecular genetics
Xia Q,Wang G,Wang H,Hu Q,Ying Z
Fri Jan 01 00:00:00 EST 2016
Reduced stress granule formation and cell death in fibroblasts with the A382T mutation of TARDBP gene: evidence for loss of TDP-43 nuclear function.
Human molecular genetics
Orrù S,Coni P,Floris A,Littera R,Carcassi C,Sogos V,Brancia C
Sat Oct 15 00:00:00 EDT 2016
Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS.
Human molecular genetics
Yamakawa M,Ito D,Honda T,Kubo K,Noda M,Nakajima K,Suzuki N
Sun Mar 15 00:00:00 EDT 2015
Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS.
Human molecular genetics
Yamakawa M,Ito D,Honda T,Kubo K,Noda M,Nakajima K,Suzuki N
Sun Mar 15 00:00:00 EDT 2015
Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity.
Human molecular genetics
Tao Z,Wang H,Xia Q,Li K,Li K,Jiang X,Xu G,Wang G,Ying Z
Fri May 01 00:00:00 EDT 2015
Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity.
Human molecular genetics
Tao Z,Wang H,Xia Q,Li K,Li K,Jiang X,Xu G,Wang G,Ying Z
Fri May 01 00:00:00 EDT 2015
Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity.
Human molecular genetics
Tao Z,Wang H,Xia Q,Li K,Li K,Jiang X,Xu G,Wang G,Ying Z
Fri May 01 00:00:00 EDT 2015
Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity.
Human molecular genetics
Tao Z,Wang H,Xia Q,Li K,Li K,Jiang X,Xu G,Wang G,Ying Z
Fri May 01 00:00:00 EDT 2015
Galectin-3 binding protein links circulating microparticles with electron dense glomerular deposits in lupus nephritis.
Lupus
Nielsen CT,Østergaard O,Rekvig OP,Sturfelt G,Jacobsen S,Heegaard NH
Thu Oct 01 00:00:00 EDT 2015
Galectin-3 binding protein links circulating microparticles with electron dense glomerular deposits in lupus nephritis.
Lupus
Nielsen CT,Østergaard O,Rekvig OP,Sturfelt G,Jacobsen S,Heegaard NH
Thu Oct 01 00:00:00 EDT 2015
SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation.
PLoS genetics
Hu S,Li J,Xu F,Mei S,Le Duff Y,Yin L,Pang X,Cen S,Jin Q,Liang C,Guo F
Wed Jul 01 00:00:00 EDT 2015
SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation.
PLoS genetics
Hu S,Li J,Xu F,Mei S,Le Duff Y,Yin L,Pang X,Cen S,Jin Q,Liang C,Guo F
Wed Jul 01 00:00:00 EDT 2015
Quantitative proteomic analysis of the metastasis-inhibitory mechanism of miR-193a-3p in non-small cell lung cancer.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Deng W,Yan M,Yu T,Ge H,Lin H,Li J,Liu Y,Geng Q,Zhu M,Liu L,He X,Yao M
Mon Dec 28 00:00:00 EST 2015
Quantitative proteomic analysis of the metastasis-inhibitory mechanism of miR-193a-3p in non-small cell lung cancer.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Deng W,Yan M,Yu T,Ge H,Lin H,Li J,Liu Y,Geng Q,Zhu M,Liu L,He X,Yao M
Mon Dec 28 00:00:00 EST 2015
Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics.
Molecular neurodegeneration
Baron DM,Kaushansky LJ,Ward CL,Sama RR,Chian RJ,Boggio KJ,Quaresma AJ,Nickerson JA,Bosco DA
Sat Aug 31 00:00:00 EDT 2013
Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics.
Molecular neurodegeneration
Baron DM,Kaushansky LJ,Ward CL,Sama RR,Chian RJ,Boggio KJ,Quaresma AJ,Nickerson JA,Bosco DA
Sat Aug 31 00:00:00 EDT 2013
Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.
PloS one
Dammer EB,Fallini C,Gozal YM,Duong DM,Rossoll W,Xu P,Lah JJ,Levey AI,Peng J,Bassell GJ,Seyfried NT
Tue Mar 26 00:00:00 EDT 2013
Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.
PloS one
Dammer EB,Fallini C,Gozal YM,Duong DM,Rossoll W,Xu P,Lah JJ,Levey AI,Peng J,Bassell GJ,Seyfried NT
Tue Mar 26 00:00:00 EDT 2013
Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.
PloS one
Dammer EB,Fallini C,Gozal YM,Duong DM,Rossoll W,Xu P,Lah JJ,Levey AI,Peng J,Bassell GJ,Seyfried NT
Tue Mar 26 00:00:00 EDT 2013
Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.
PloS one
Dammer EB,Fallini C,Gozal YM,Duong DM,Rossoll W,Xu P,Lah JJ,Levey AI,Peng J,Bassell GJ,Seyfried NT
Tue Mar 26 00:00:00 EDT 2013
Roles of ataxin-2 in pathological cascades mediated by TAR DNA-binding protein 43 (TDP-43) and Fused in Sarcoma (FUS).
The Journal of biological chemistry
Nihei Y,Ito D,Suzuki N
Fri Nov 30 00:00:00 EST 2012
Roles of ataxin-2 in pathological cascades mediated by TAR DNA-binding protein 43 (TDP-43) and Fused in Sarcoma (FUS).
The Journal of biological chemistry
Nihei Y,Ito D,Suzuki N
Fri Nov 30 00:00:00 EST 2012
Nuclear transport impairment of amyotrophic lateral sclerosis-linked mutations in FUS/TLS.
Annals of neurology
Ito D,Seki M,Tsunoda Y,Uchiyama H,Suzuki N
Sat Jan 01 00:00:00 EST 2011
Nuclear transport impairment of amyotrophic lateral sclerosis-linked mutations in FUS/TLS.
Annals of neurology
Ito D,Seki M,Tsunoda Y,Uchiyama H,Suzuki N
Sat Jan 01 00:00:00 EST 2011
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43.
The Journal of biological chemistry
Nishimoto Y,Ito D,Yagi T,Nihei Y,Tsunoda Y,Suzuki N
Fri Jan 01 00:00:00 EST 2010
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43.
The Journal of biological chemistry
Nishimoto Y,Ito D,Yagi T,Nihei Y,Tsunoda Y,Suzuki N
Fri Jan 01 00:00:00 EST 2010
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43.
The Journal of biological chemistry
Nishimoto Y,Ito D,Yagi T,Nihei Y,Tsunoda Y,Suzuki N
Fri Jan 01 00:00:00 EST 2010
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43.
The Journal of biological chemistry
Nishimoto Y,Ito D,Yagi T,Nihei Y,Tsunoda Y,Suzuki N
Fri Jan 01 00:00:00 EST 2010
RNA metabolism protein
