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GABA(A) R gamma-3 Polyclonal Antibody
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Product Details
OSG00090W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from extracellular domain (aa region 150-250) of human GABA(A) R gamma-3 conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: GABRG3.
Target Information
GABRG3 is a family of proteins involved in the GABAergic neurotransmission of the mammalian central nervous system. GABRG3 is a member of the GABA-A receptor gene family of heteromeric pentameric ligand-gated ion channels through which GABA, the major inhibitory neurotransmitter in the mammalian brain, acts. GABA-A receptors are the site of action of a number of important pharmacologic agents including barbiturates, benzodiazepines, and ethanol (summary by Whiting et al., 1999). For additional general information about the GABA-A receptor gene family, see GABRA1 (MIM 137160).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CAE2; ECA2; GABA(A) receptor subunit gamma-3; GABA(G) receptor; GABA(G) receptor, gamma 3; GABA-alpha receptor gamma-3 subunit; GABAAR subunit gamma-3; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, gamma 3; gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 3; gamma-aminobutyric acid A receptor, gamma 3; Gamma-aminobutyric acid receptor subunit gamma-3; gamma-aminobutyric acid type A receptor gamma3 subunit; GEFSP3
Gene Aliases: B230362M20Rik; Gabrg-3; GABRG3
UniProt ID: (Human) Q99928, (Rat) P28473, (Mouse) P27681
Entrez Gene ID: (Human) 2567, (Rat) 79211, (Mouse) 14407
transmembrane signaling receptor activity
GABA-A receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
chloride channel activity
benzodiazepine receptor activity
GABA-gated chloride ion channel activity
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
ligand-gated ion channel
ion transport
chloride transport
gamma-aminobutyric acid signaling pathway
response to xenobiotic stimulus
ion transmembrane transport
synaptic transmission, GABAergic
regulation of postsynaptic membrane potential
chloride transmembrane transport
inhibitory synapse assembly
response to drug
transport
signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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