PA1-33115 detects GADD34 from human samples.
PA1-33115 has been successfully used in ELISA and Western blot applications.
The PA1-33115 immunogen is: Peptide sequence AAALDLSGRRG corresponding to the C-terminus of GADD34 (NP_055145).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GADD34; Growth arrest and DNA damage-inducible protein GADD34; growth arrest and DNA-damage-inducible 34; Myeloid differentiation primary response protein MyD116 homolog; Protein phosphatase 1 regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A; protein phosphatase 1, regulatory subunit 15A
Gene Aliases: GADD34; PPP1R15A
UniProt ID: (Human) O75807
Entrez Gene ID: (Human) 23645