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Proteintech
GADD45A Polyclonal Antibody
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Product Details
13747-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GADD45A Fusion Protein Ag4687 (5-165 aa encoded by BC011757)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EFSAGEQKT ERMDKVGDAL EEVLSKALSQ RTITVGVYEA AKLLNVDPDN VVLCLLAADE DDDRDVALQI HFTLIQAFCC ENDINILRVS NPGRLAELLL LETDAGPAAS EGAEQPPDLH CVLVTNPHSS QWKDPALSQL ICFCRESRYM DQWVPVINLP ER (5-165 aa encoded by BC011757)
Target Information
GADD45 alpha, beta and gamma are an evolutionarily conserved, homologous family of nuclear proteins that function as stress sensors for cellular physiological and environmental damage. GADD45 proteins are required for the activation of the G2/M checkpoint induced by UV radiation or alkylating agents. GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2-cyclin B1 kinase. GADD45 forms a complex with p21 and Cdc2, and may serve as core for interaction with other cell cycle regulators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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