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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GADD45A|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine based on sequence homology.
GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45A gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DDIT-1; DDIT1; DNA damage-inducible transcript 1 protein; DNA damage-inducible transcript-1; DNA-damage-inducible transcript 1; GADD45; GADD45A; growth arrest and DNA-damage-inducible 45 alpha; Growth arrest and DNA-damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible, alpha
DDIT1; GADD45; GADD45A