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Immunogen sequence: GGSVEILPCS RVGHIYQNQD SHSPLDQEAT LRNRVRIAET WLGSFKETFY KHSPEAFSLS KAEKPDCMER LQLQRRLGCR TFHWFLANVY PELYPSEPRP SFSGKLHNTG LG
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 61%.
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GalNAc-T-like protein 2; polypeptide GalNAc transferase 15; Polypeptide GalNAc transferase-like protein 2; polypeptide N-acetylgalactosaminyltransferase 13; Polypeptide N-acetylgalactosaminyltransferase 15; Polypeptide N-acetylgalactosaminyltransferase-like protein 2; pp-GaNTase-like protein 2; pregnancy-induced hypertension syndrome-related protein 5; Protein-UDP acetylgalactosaminyltransferase-like protein 2; UDP-GalNAc transferase T15; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2
Gene Aliases: GALNACT15; GALNT13; GALNT15; GALNT7; GALNTL2; PIH5; pp-GalNAc-T15; UNQ770/PRO1564
UniProt ID: (Human) Q8N3T1
Entrez Gene ID: (Human) 117248
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