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Invitrogen
GARS Polyclonal Antibody
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FIGURE: 1 / 5
GARS Antibody (PA5-106927) in IHC (P)
Immunohistochemistry analysis of GARS in human kidney cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with GARS polyclonal antibody (Product # PA5-106927) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-106927
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GARS(Accession P41250), corresponding to amino acid residues Q623-D673.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total GARS.
Target Information
GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This protein is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. The protein has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 6.1.1.14; AIR synthase; AIRS; AP-4-A synthetase; Ap4A synthetase; Charcot-Marie-Tooth neuropathy 2D; Charcot-Marie-Tooth neuropathy, neuronal type, D; Diadenosine tetraphosphate synthetase; EC 2.1.2.29; GAR transformylase; GART; GARTF; glycine tRNA ligase; Glycine--tRNA ligase; Glycyl-tRNA synthetase; Glycyl-tRNA synthetase 1; GlyRS; MGC47764; PAIS; PGFT; PRGS; storage granule protein 23
Gene Aliases: CMT2D; DSMAV; GARS; GARS1; Gena201; GENA202; GlyRS; HMN5; Nmf249; RGD1559871; Sgrp23; SMAD1
UniProt ID: (Human) P41250, (Rat) Q5I0G4, (Mouse) Q9CZD3
Entrez Gene ID: (Human) 2617, (Rat) 297113, (Mouse) 353172
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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