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Active Motif
GATA-4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
39893
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
This GATA-4 antibody was raised against a peptide derived from the C-terminus of human GATA-4.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.66 mg/mL
Amount
66 µg
Purification
Antigen affinity chromatography
Storage buffer
70mM tris, pH 8, with 105mM NaCl, 0.07mM EDTA, 31mM glycine, 30% glycerol
Contains
0.035% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
GATA4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in the gene encoding GATA4 have been associated with cardiac septal defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GAT4; GATA-binding factor 4; MGC126629; putative; unnamed protein product
Gene Aliases: ASD2; Gata-4; TACHD; TOF; VSD1
UniProt ID: (Human) P43694, (Mouse) Q08369
Entrez Gene ID: (Human) 2626, (Mouse) 14463
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
transcription coactivator binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
protein kinase binding
sequence-specific DNA binding
NFAT protein binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
co-SMAD binding
DNA-binding transcription factor binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
gastrulation with mouth forming second
endoderm formation
heart looping
heart morphogenesis
outflow tract morphogenesis
aortic valve morphogenesis
atrioventricular valve morphogenesis
atrioventricular valve formation
mitral valve formation
tricuspid valve formation
endocardial cushion development
cardiac right ventricle morphogenesis
ventricular cardiac muscle tissue development
cardiac septum development
ventricular septum development
atrial septum primum morphogenesis
atrial septum secundum morphogenesis
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell-cell signaling
spermatogenesis
heart development
male gonad development
response to xenobiotic stimulus
response to mechanical stimulus
tissue development
regulation of gene expression
negative regulation of autophagy
positive regulation of vascular endothelial growth factor production
positive regulation of gene expression
negative regulation of gene expression
negative regulation of cardiac muscle cell apoptotic process
cardiac muscle hypertrophy in response to stress
signal transduction involved in regulation of gene expression
positive regulation of BMP signaling pathway
response to retinoic acid
response to vitamin A
embryonic heart tube development
embryonic heart tube anterior/posterior pattern specification
tube morphogenesis
skeletal muscle cell differentiation
atrioventricular canal development
wound healing
negative regulation of apoptotic process
response to estrogen
cell fate commitment
positive regulation of angiogenesis
positive regulation of cell cycle
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract morphogenesis
embryonic morphogenesis
embryonic foregut morphogenesis
cardiac muscle tissue development
regulation of developmental process
regulation of multicellular organismal process
cardiac muscle cell differentiation
Sertoli cell differentiation
regulation of cardiac muscle cell proliferation
positive regulation of cardiac muscle cell proliferation
transdifferentiation
atrial septum morphogenesis
lung morphogenesis
lung lobe formation
diaphragm morphogenesis
intestinal epithelial cell differentiation
vasculogenesis involved in coronary vascular morphogenesis
cardiac muscle tissue regeneration
cell growth involved in cardiac muscle cell development
cellular response to glucose stimulus
cellular response to gonadotropin stimulus
cellular response to follicle-stimulating hormone stimulus
epithelial cell fate commitment
seminiferous tubule development
regulation of cardiac muscle cell contraction
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
negative regulation of connective tissue replacement
negative regulation of apoptotic signaling pathway
atrioventricular node development
cardiac ventricle morphogenesis
endoderm development
anatomical structure morphogenesis
cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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