PA1-100 specifically detects GATA2 and does not cross-react with GATA1 or GATA3.
This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.
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Protein Aliases: Endothelial transcription factor GATA-2; GATA-binding protein 2
Gene Aliases: DCML; Gata-2; GATA2; IMD21; MONOMAC; NFE1B