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Invitrogen
GC Polyclonal Antibody
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FIGURE: 1 / 1
GC Antibody (PA5-96403) in WB
Western blot analysis of GC in extracts of various cell lines. Samples were incubated with GC Polyclonal antibody (Product # PA5-96403) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-96403
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 324-493 of human Vitamin D Binding protein (NP_0011912361)
Conjugate
Form
Liquid
Concentration
1.61 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AMDVFVCTYF MPAAQLPELP DVELPTNKDV CDPGNTKVMD KYTFELSRRT HLPEVFLSKV LEPTLKSLGE CCDVEDSTTC FNAKGPLLKK ELSSFIDKGQ ELCADYSENT FTEYKKKLAE RLKAKLPDAT PTELAKLVNK HSDFASNCCS INSPPLYCDS EIDAELKNIL; Positive Samples: A-431, 293T, A-549, NCI-H460, A375, SH-SY5Y, Mouse liver
Target Information
GC (vitamin D-binding protein) is involved in vitamin D transport/storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DBP; DBP-maf; DBP/ VDBG; epididymis secretory protein Li 51; Gc; Gc globulin; Gc protein-derived macrophage activating factor; Gc-globulin; Gc-MAF; Group specific component vitamin D binding protein; Group-specific component; group-specific component (vitamin D binding protein); hDBP; V VDB; VDB; Vitamin D binding alpha globulin; vitamin D-binding alpha-globulin; Vitamin D-binding protein; Vitamin D-binding protein-macrophage activating factor
Gene Aliases: DBP; DBP/GC; GC; Gc-MAF; GcMAF; GRD3; HEL-S-51; VDB; VDBG; VDBP
UniProt ID: (Human) P02774, (Mouse) P21614
Entrez Gene ID: (Human) 2638, (Mouse) 14473
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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