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GCHFR Antibody (PA5-115273) in IHC (P)
Immunohistochemistry analysis of GCHFR in human colorectal cancer and adjacent normal tissues. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115273) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-115273
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GCHFR(Accession P30047), corresponding to amino acid residues M1-Y45.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2899909
Product Specific Information
Antibody detects endogenous levels of total GCHFR.
Target Information
Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GFRP; GTP cyclohydrolase 1 feedback regulatory protein; GTP cyclohydrolase I feedback regulatory protein; p35
Gene Aliases: 2010323F13Rik; GCHFR; GFRP; HsT16933; P35
UniProt ID: (Human) P30047, (Mouse) P99025, (Rat) P70552
Entrez Gene ID: (Human) 2644, (Mouse) 320415, (Rat) 171128
nitric oxide biosynthetic process
negative regulation of biosynthetic process
neurotransmitter metabolic process
negative regulation of GTP cyclohydrolase I activity
regulation of nitric-oxide synthase activity
protein heterooligomerization
protein complex assembly
regulation of nitric oxide biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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