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Invitrogen
GCNF Polyclonal Antibody
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Product Details
PA5-34020
Product Specifications
Species Reactivity
Bat,
Bovine,
Dog,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Pig,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 18 amino acid peptide from ligand-binding domain of human NR6A1 / GCNF.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses at least alternatively spliced transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GCNF; Germ cell nuclear factor; h hRTR; mGCNF; nuclear receptor subfamily 5, group A, member 1; Nuclear receptor subfamily 6 group A member 1; nuclear receptor subfamily 6, group A, member 1; putative new variant; retinoic acid receptor-related testis-associated receptor; Retinoid receptor-related testis-specific receptor; RTR; steroidogenic factor 1
Gene Aliases: 1700113M01Rik; CT150; GCNF; GCNF1; hGCNF; hRTR; I79_020174; NCNF; NR5A1; NR61; NR6A1; RTR; Sf1
UniProt ID: (Human) Q15406, (Pig) A0P8Z4, (Mouse) Q64249
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
zinc ion binding
estrogen response element binding
protein homodimerization activity
sequence-specific DNA binding
metal ion binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
steroid hormone receptor activity
protein binding
C4 zinc finger nuclear receptor
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
gamete generation
intracellular receptor signaling pathway
positive regulation of transcription from RNA polymerase II promoter
positive regulation of mesenchymal stem cell differentiation
multicellular organism development
spermatogenesis
cell differentiation
transcription, DNA-templated
transcription from RNA polymerase II promoter
steroid hormone mediated signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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