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Proteintech
GDF1 Polyclonal Antibody
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Product Details
28345-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: LFRRRDPQET RSGSRRTSPG VTLQPCHVEE LGVAGNIVRH IPDRGAPTRA SEPASAAGHC PEWTVVFDLS AVEPAERPSR ARLELRFAAA AAAAPEGGWE LSVAQAGQGA GADPGPVLLR QLVPALGPPV RAELLGAAWA RNASWPRSLR LALALRPRAP AACARLAEAS LLLVTLDPRL CHPLARPRRD AEPVLGGGPG GACRARRLY
Target Information
Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Embryonic growth/differentiation factor 1; GDF-1
Gene Aliases: AI385651; DORV; DTGA3; Gdf-1; GDF1; RAI
UniProt ID: (Human) P27539, (Mouse) P20863
Entrez Gene ID: (Human) 2657, (Mouse) 14559, (Rat) 306351
positive regulation of pathway-restricted SMAD protein phosphorylation
BMP signaling pathway
regulation of apoptotic process
regulation of MAPK cascade
cell development
SMAD protein signal transduction
in utero embryonic development
signal transduction
endoderm development
mesoderm development
growth
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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