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Proteintech
GFM2 Polyclonal Antibody
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Product Details
16941-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GFM2 Fusion Protein Ag10530 (430-779 aa encoded by BC015712)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GNIALTVGL KHTATGDTIV SSKSSALAAA RRAEREGEKK HRQNNEAERL LLAGVEIPEP VFFCTIEPPS LSKQPDLEHA LKCLQREDPS LKVRLDPDSG QTVLCGMGEL HIEIIHDRIK REYGLETYLG PLQVAYRETI LNSVRATDTL DRTLGDKRHL VTVEVEARPI ETSSVMPVIE FEYAESINEG LLKVSQEAIE NGIHSACLQG PLLGSPIQDV AITLHSLTIH PGTSTTMISA CVSRCVQKAL KKADKQVLEP LMNLEVTVAR DYLSPVLADL AQRRGNIQEI QTRQDNKVVI GFVPLAEIMG YSTVLRTLTS GSATFALELS TYQAMNPQDQ NTLLNRRSGL T (430-779 aa encoded by BC015712)
Target Information
GFM2 is involved in mitochondrial translation, which is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. In Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EF-G2mt; Elongation factor G 2, mitochondrial; Elongation factor G2; G elongation factor; G elongation factor mitochondrial 2; hEFG2; mitochondrial elongation factor G2; mitochondrial ribosome recycling factor 2; mitochondrial ribosome-releasing factor 2; ribosome releasing factor 2; Ribosome-releasing factor 2, mitochondrial; RRF2mt; unnamed protein product
Gene Aliases: EF-G2mt; EFG2; GFM2; hEFG2; mEF-G 2; MRRF2; MST027; MSTP027; RRF; RRF2; RRF2mt
UniProt ID: (Human) Q969S9
Entrez Gene ID: (Human) 84340
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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