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GFR alpha 3 Polyclonal Antibody
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FIGURE: 1 / 2
GFR alpha 3 Antibody (200-401-BK7) in IHC (P)
Immunohistochemistry of Rabbit anti-GFR alpha 3 antibody. Tissue: mouse heart tissue. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: anti-GFR alpha 3 antibody at 10 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: GFR alpha 3 is membrane bound. Staining: GFR alpha 3 as precipitated brown... View More
Product Details
200-401-BK7
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-GFR alpha 3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid peptide near the internal region of murine GFR alpha 3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Ion-exchange chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
GFRa-3 binds persephin, thus, persephin, GFRa-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDNF family receptor alpha-3; GDNF receptor alpha-3; GDNF receptor alpha-3 variant; GDNF-family receptor alpha 3; GDNFR-alpha-3; GFR alpha-3; GFR-alpha-3; GFRalpha3; glial cell line derived neurotrophic factor family receptor alpha 3; glial cell line-derived neurotrophic factor receptor alpha-3; GPI-linked receptor; unnamed protein product
Gene Aliases: GDNFR3; GFRA3; GFRalpha3; UNQ339/PRO538/PRO3664; Y15110
UniProt ID: (Human) O60609, (Mouse) O35118
Entrez Gene ID: (Human) 2676, (Mouse) 14587, (Rat) 84422
neuron migration
signal transduction
nervous system development
axon guidance
peripheral nervous system development
glial cell-derived neurotrophic factor receptor signaling pathway
sympathetic nervous system development
neuron development
transmembrane receptor protein tyrosine kinase signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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