Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: DNLTQVINLY KQLVRGEEVN GDATAGSIPG STSALLDLSG LDLPPAGTTY PAMPTRP^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 91%.
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADP-ribosylation factor binding protein 1; ADP-ribosylation factor-binding protein GGA1; gamma-adaptin related protein 1; Gamma-adaptin-related protein 1; golgi-associated, gamma adaptin ear containing, ARF binding protein 1; Golgi-localized, gamma ear-containing, ARF-binding protein 1
Gene Aliases: GGA1
UniProt ID: (Human) Q9UJY5
Entrez Gene ID: (Human) 26088
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support