Recommended positive controls: PC-3, SK-N-SH.
Predicted reactivity: Mouse (94%), Rat (94%), Zebrafish (82%), Xenopus laevis (87%), Rhesus Monkey (97%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase; Geranylgeranyl pyrophosphate synthase; Geranyltranstransferase; GGPP synthase; GGPPSase
Gene Aliases: GGPPS; GGPPS1; GGPS1
UniProt ID: (Human) O95749
Entrez Gene ID: (Human) 9453