This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.
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Protein Aliases: Gastric inhibitory polypeptide; GIP; Glucose-dependent insulinotropic polypeptide; Incretin hormone; Rabbit Anti GIP
Gene Aliases: GIP
UniProt ID: (Human) P09681
Entrez Gene ID: (Human) 2695