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Invitrogen
GLAST Polyclonal Antibody
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FIGURE: 1 / 1
GLAST Antibody (PA5-34197) in IHC (P)
Immunohistochemistry analysis of GLAST in human brain, cerebellum (molecular layer and Purkinje layer). Samples were incubated with GLAST polyclonal antibody (Product # PA5-34197). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-34197
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 15 amino acid peptide from cytoplasmic domain of human SLC1A3 / GLAST.
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Mouse, Hamster, Elephant, Panda, Horse (93%) Marmoset, Rat, Pig (87%).
Target Information
This gene encodes a member of a member of a high affinity glutamate transporter family. Mutations in this gene are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EAAT-1; Excitatory amino acid transporter 1; FLJ25094; GLAST-1; Sodium-dependent glutamate/aspartate transporter 1; solute carrier family 1 (glial high affinity glutamate transporter), member 3; Solute carrier family 1 member 3
Gene Aliases: EA6; EAAT1; GLAST; GLAST1; SLC1A3
UniProt ID: (Human) P43003
Entrez Gene ID: (Human) 6507
neurotransmitter uptake
positive regulation of defense response to virus by host
amino acid transmembrane transport
glutamate biosynthetic process
ion transport
chemical synaptic transmission
sensory perception of sound
response to light stimulus
gamma-aminobutyric acid biosynthetic process
response to wounding
glutamate secretion
cranial nerve development
auditory behavior
response to drug
malate-aspartate shuttle
response to antibiotic
cell morphogenesis involved in neuron differentiation
positive regulation of synaptic transmission
neuromuscular process controlling balance
L-glutamate import
D-aspartate import
L-glutamate transmembrane transport
mitophagy in response to mitochondrial depolarization
xenophagy
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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