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Invitrogen
GLMN Polyclonal Antibody
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FIGURE: 1 / 1
GLMN Antibody (PA5-88301) in WB
Western blot analysis of GLMN in extracts of various cell lines. Samples were incubated with GLMN Polyclonal antibody (Product # PA5-88301) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-88301
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 405-594 of human GLMN (NP_4445041)
Conjugate
Form
Liquid
Concentration
3.56 mg/mL
Amount
356 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RCLLNTSNHS GVEAFIIQNI KNQIDMSLKR TRNNKWFTGP QLISLLDLVL FLPEGAETDL LQNSDRIMAS LNLLRYLVIK DNENDNQTGL WTELGNIENN FLKPLHIGLN MSKAHYEAEI KNSQEAQKSK DLCSITVSGE EIPNMPPEMQ LKVLHSALFT FDLIESVLAR VEELIEIKTK STSEENIGIK; Positive Samples: A-549, U-87MG, HepG2, Mouse testis
Target Information
This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FAP; FK506-binding protein-associated protein; FKBP-associated protein; Glomulin; unnamed protein product
Gene Aliases: 9330160J16Rik; AW227515; FAP; FAP48; FAP68; FKBPAP; GLML; GLMN; GVM; VMGLOM
UniProt ID: (Human) Q92990, (Mouse) Q8BZM1
Entrez Gene ID: (Human) 11146, (Mouse) 170823
vasculogenesis
positive regulation of cytokine production
neural tube closure
cell surface receptor signaling pathway
negative regulation of cell proliferation
regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of interleukin-2 production
regulation of gene expression, epigenetic
negative regulation of T cell proliferation
positive regulation of phosphorylation
muscle cell differentiation
circulatory system development
negative regulation of protein ubiquitination
negative regulation of catalytic activity
positive regulation of interleukin-2 biosynthetic process
positive regulation of cytokine secretion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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