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Invitrogen
GLP2R Polyclonal Antibody
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FIGURE: 1 / 1
GLP2R Antibody (PA5-76959) in WB
Frontiers in endocrinology 2022 -
Figure 1 Expression and activation of proglucagon-derived peptide receptors in murine osteoblasts. (A) Relative expression of glucagon receptor ( Gcgr ), glucagon-like peptide-1 receptor ( Glp1r ), and glucagon-like peptide-2 receptor ( Glp2r ) was investigated by qPCR. CHO-K1 cells transfected with the empty pcDNA3.1 vector was used as negative control. CHO-K1 cells transfected with the pcDNA 3.1 vector en... View More
Product Details
PA5-76959
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 460-553 of human GLP2R.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.03% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: G protein-coupled receptor GLP2R; GLP-2 receptor; GLP-2-R; GLP-2R; Glp2 receptor; Glucagon-like peptide 2 receptor
Gene Aliases: 9530092J08Rik; GLP-2; GLP2R
UniProt ID: (Human) O95838, (Mouse) Q5IXF8
Entrez Gene ID: (Human) 9340, (Mouse) 93896
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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