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QED Bioscience
GLUT10 Polyclonal Antibody
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Product Details
28103-100UG
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 367-385 (ILSTAKKTKPHPRSGDPSA) of human GLUT10 conjugated to KLH at the N-terminus.
Conjugate
Form
Liquid
Concentration
0.5-1.0 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
2-8°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Non-insulin-dependent diabetes mellitus (NIDDM) is a multifactoral disease with both environmental and genetics causes. Genome-wide screening procedures have identified several susceptibility loci for NIDDM within the human genome. A putative sugar transporter that has been localized to human chromosome 20q12-q13.1, one of the genomic loci associated with NIDDM. Because of the strong resemblance of this novel protein to members of the mammalian facilitative glucose transporter family (GLUT), the protein is known as GLUT10 (HGMW-approved gene symbol SLC2A10). Data suggests that GLUT10 an excellent candidate for a susceptibility gene involved in NIDDM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: facilitative glucose transporter GLUT10; Glucose transporter type 10; GLUT-10; GLUT11; MGC118830; MGC118833; SLC2A11-a; SLC2A11-c; solute carrier family 2 (facilitated glucose transporter), member 10; Solute carrier family 2, facilitated glucose transporter member 10; unnamed protein product
Gene Aliases: ATORS; ATS; GLUT10; SLC2A10
UniProt ID: (Human) O95528
Entrez Gene ID: (Human) 81031
hexose transport
positive regulation of gene expression
negative regulation of gene expression
galactose transport
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of connective tissue growth factor production
skin development
cell redox homeostasis
transmembrane transport
artery development
dehydroascorbic acid transport
circulatory system development
embryonic skeletal joint development
glucose import across plasma membrane
transport across blood-brain barrier
hydrogen ion transmembrane transport
negative regulation of proteoglycan biosynthetic process
positive regulation of proteoglycan biosynthetic process
regulation of extracellular matrix organization
glucose transmembrane transport
negative regulation of integrin-mediated signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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