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Invitrogen
GLUT3 Polyclonal Antibody
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FIGURE: 1 / 11
GLUT3 Antibody (PA5-99486) in ICC/IF
Immunofluorescent analysis of GLUT3 in LOVO. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with GLUT3 polyclonal antibody (Product # PA5-99486) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Product Details
PA5-99486
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SLC2A3(Accession P11169), corresponding to amino acid residues T462-V496.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total GLUT3.
Target Information
Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF1 induced signaling. GLUT3 is detectable in a few normal cell type spermatids in testis with active spermatogenesis, placental trophoblast membranes, and neurons in brain. GLUT3 staining is also detectable in human cancers including those of the ovary, lung, and testis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ90380; glucose transporter 3; Glucose transporter type 3, brain; glucose transporter-like protein; GLUT-3; SLC2A3; solute carrier family 2 (facilitated glucose transporter), member 3; Solute carrier family 2 A3 (neuron glucose transporter); Solute carrier family 2, facilitated glucose transporter member 3; solute carrier family 2, member 2; solute carrier family 2, member 3; unnamed protein product
Gene Aliases: AA408729; AL023014; AL024341; AU040424; C78366; Glut-3; GLUT3; SLC2A3
UniProt ID: (Human) P11169, (Mouse) P32037, (Rat) Q07647
Entrez Gene ID: (Human) 6515, (Mouse) 20527, (Rat) 25551
fructose transmembrane transporter activity
galactose transmembrane transporter activity
protein binding
glucose binding
transmembrane transporter activity
dehydroascorbic acid transporter activity
D-glucose transmembrane transporter activity
transporter activity
sugar:proton symporter activity
glucose transmembrane transporter activity
monosaccharide transmembrane transporter activity
galactoside binding
kinase binding
substrate-specific transmembrane transporter activity
xylose binding
transport
carbohydrate transport
glucose transport
proton transport
hexose transmembrane transport
glucose import
transmembrane transport
dehydroascorbic acid transport
cation transmembrane transport
carbohydrate metabolic process
fructose transport
galactose transport
L-ascorbic acid metabolic process
glucose import across plasma membrane
transport across blood-brain barrier
glucose transmembrane transport
response to glucose
monosaccharide transport
negative regulation of apoptotic process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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