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Active Motif
GLYR1 Polyclonal Antibody
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Product Details
65693ACTMOTIF
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
This antibody was raised against a peptide within the C-terminal region of human GLYR1.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Purification
Affinity chromatography
Storage buffer
70mM tris with 0.07mM EDTA, 30% glycerol, 31mM glycine, 105mM NaCl
Contains
0.035% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
GLYR1 may have oxidoreductase activity. It regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. It indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. It is recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-hydroxyisobutyrate dehydrogenase-like protein; Cytokine-like nuclear factor N-PAC; Glyoxylate reductase 1 homolog; hNDF; NPAC; nuclear protein 60 kDa; nuclear protein 60kDa; Nuclear protein NP60; Nuclear protein of 60 kDa; Nucleosome-destabilizing factor; Putative oxidoreductase GLYR1; unnamed protein product
Gene Aliases: BM045; GLYR1; HIBDL; hNDF; N-PAC; NDF; NP60; NPAC
UniProt ID: (Human) Q49A26
Entrez Gene ID: (Human) 84656
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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