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Invitrogen
GM130 Polyclonal Antibody
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Product Details
PA1-077
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Bovine,
C. elegans,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues G(368) Q V M E S V R Q L Q M E R D K(383) of human GM130.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-077 detects GM130 from human samples.
PA1-077 has been successfully used in Western blot, flow cytometry, and immunofluorescence procedures. By Western blot, PA1-077 detects a ~135 kDa band representing GM130 from Hela cell lysate.
The PA1-077 immunogen is a synthetic peptide corresponding to residues G(368) Q V M E S V R Q L Q M E R D K(383) of human GM130.
PA1-077 can be used with blocking peptide PEP-296.
Target Information
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 130 kDa cis-Golgi matrix protein; GM130; GM130 autoantigen; golgi autoantigen, golgin subfamily a, 2; Golgi matrix protein GM130; Golgin subfamily A member 2; Golgin-95; RP11-395P17.5; SY11 protein
Gene Aliases: GM130; GOLGA2
UniProt ID: (Human) Q08379
Entrez Gene ID: (Human) 2801
protein glycosylation
ER to Golgi vesicle-mediated transport
microtubule nucleation
asymmetric cell division
negative regulation of autophagy
negative regulation of protein binding
COPII vesicle coating
spindle assembly
protein homotetramerization
centrosome organization
positive regulation of protein glycosylation
Golgi ribbon formation
Golgi disassembly
spindle assembly involved in meiosis
mitotic spindle assembly
cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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