This Antibody was verified by Cell Treatment to ensure that the antibody binds to the antigen stated. View Details
PA1-077 detects GM130 from human samples.
PA1-077 has been successfully used in Western blot, flow cytometry, and immunofluorescence procedures. By Western blot, PA1-077 detects a ~135 kDa band representing GM130 from Hela cell lysate.
The PA1-077 immunogen is a synthetic peptide corresponding to residues G(368) Q V M E S V R Q L Q M E R D K(383) of human GM130.
PA1-077 can be used with blocking peptide PEP-296.
GM130 is a putative cis-Golgi matrix protein that belongs to the golgin family of autoantigens possessing extensive coiled-coil domains. This protein interacts with GRASP65 and acts as a receptor for the vesicle docking protein p115 during vesicle fusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 130 kDa cis-Golgi matrix protein; GM130; GM130 autoantigen; golgi autoantigen, golgin subfamily a, 2; Golgi matrix protein GM130; Golgin subfamily A member 2; Golgin-95; SY11 protein
Gene Aliases: GM130; GOLGA2
UniProt ID: (Human) Q08379
Entrez Gene ID: (Human) 2801
Molecular Function: membrane traffic protein