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Product Details
PA5-142618
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
0.3 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Rat |
Host/Isotype |
Goat / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Peptide with sequence C-TTGNYRIESVLS. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
TBS, pH 7.3, with 0.5% BSA |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Additional Information: This antibody is expected to recognize isoform 1 (NP_000396.2) only.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
Target Information
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ganglioside GM2 activator; GM2 ganglioside activator protein
Entrez Gene ID: (Rat) 282838
Molecular Function:
transfer/carrier protein
ganglioside metabolic process
ganglioside catabolic process
lipid transport
learning or memory
oligosaccharide catabolic process
lipid storage
positive regulation of catalytic activity
neurological system process
neuromuscular process controlling balance
positive regulation of hydrolase activity
membrane fusion
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