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Recommended positive controls: 293T, A431, HeLa, Raji, mouse brain, rat brain.
Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (90%), Xenopus laevis (92%), Pig (98%), Chicken (97%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMF in astrocytes has been shown to enhance brain-derived neurotrohic factor (BDNF) production. GMF expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF. Through BDNF production, GMF appears to play a role in neuroprotection. In thymoma, T-cell development is maintained by GMF; being produced by the tumor cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA for thyroid hormone receptor binding site (276bp); Glia maturation factor beta; glia maturation factor, beta; GMF-beta
Gene Aliases: 3110001H22Rik; 3110001O16Rik; AI851627; C79176; D14Ertd630e; GMF; GMFB
Molecular Function: intercellular signal molecule