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Product Details
PA5-103879
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:3,000 | - |
Immunocytochemistry (ICC/IF) |
1:100-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human GNG7(Accession O60262), corresponding to amino acid residues V28-N57. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2853211 |
Target Information
GNG7 is a Guanine nucleotide-binding protein (G proteins) and are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilization of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: guanine nucleotide binding protein (G protein), gamma 7; guanine nucleotide binding protein (G protein), gamma 7 subunit; guanine nucleotide binding protein, gamma 7; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
Gene Aliases: AI840417; GNG7; GNGT7
UniProt ID: (Human) O60262, (Rat) P43425, (Mouse) Q61016
Entrez Gene ID: (Human) 2788, (Rat) 58979, (Mouse) 14708
Molecular Function:
heterotrimeric G-protein
G-protein coupled receptor signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
cellular response to glucagon stimulus
behavioral fear response
receptor guanylyl cyclase signaling pathway
locomotory behavior
biological_process
regulation of adenylate cyclase activity
signal transduction
Performance Guarantee
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