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Fabgennix
GPCR GPR43/FFAR2 Polyclonal Antibody
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Product Details
FFAR2-201AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 250-300 on human free fatty acid receptor 2 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR43 is a member of this family (subfamily carboxylic acid). It expression has been reported primarily in immune cells including monocytes and neutrophils. An EST has been isolated from a human pancreatic library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: fatty acid receptor 2; free fatty acid activated receptor 2; Free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; Leukocyte-specific STAT-induced GPCR
Gene Aliases: FFA2; FFA2R; FFAR2; GPCR43; GPR43; Lssig
UniProt ID: (Human) O15552, (Rat) Q76EI6, (Mouse) Q8VCK6
Entrez Gene ID: (Human) 2867, (Rat) 292794, (Mouse) 233079
leukocyte chemotaxis involved in inflammatory response
immune system process
mucosal immune response
regulation of acute inflammatory response
positive regulation of cytokine production involved in immune response
cell surface pattern recognition receptor signaling pathway
positive regulation of acute inflammatory response to non-antigenic stimulus
inflammatory response
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
lipid storage
positive regulation of insulin secretion
positive regulation of chemokine production
positive regulation of interleukin-8 production
glucose homeostasis
fat cell differentiation
negative regulation of insulin secretion
cellular response to fatty acid
regulation of peptide hormone secretion
ligand-gated ion channel signaling pathway
biological_process
positive regulation of interleukin-8 secretion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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