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Proteintech
GPD1 Polyclonal Antibody
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Product Details
13451-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GPD1 Fusion Protein Ag4278 (1-349 aa encoded by BC032234)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASKKVCIV GSGNWGSAIA KIVGGNAAQL AQFDPRVTMW VFEEDIGGKK LTEIINTQHE NVKYLPGHKL PPNVVAVPDV VQAAEDADIL IFVVPHQFIG KICDQLKGHL KANATGISLI KGVDEGPNGL KLISEVIGER LGIPMSVLMG ANIASEVADE KFCETTIGCK DPAQGQLLKE LMQTPNFRIT VVQEVDTVEI CGALKNVVAV GAGFCDGLGF GDNTKAAVIR LGLMEMIAFA KLFCSGPVSS ATFLESCGVA DLITTCYGGR NRKVAEAFAR TGKSIEQLEK ELLNGQKLQG PETARELYSI LQHKGLVDKF PLFMAVYKVC YEGQPVGEFI HCLQNHPEHM (1-349 aa encoded by BC032234)
Target Information
This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: glycerol 3-phosphate dehydrogenase; glycerol phosphate dehydrogenase 1, cytoplasmic adult; glycerol-3-phosphate dehydrogenase 1 (soluble); Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic; glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; glycerolphosphate dehydrogenase 1, cytoplasmic adult; glycerophosphate dehydrogenase; GPD-C; GPDH-C
Gene Aliases: AI747587; Gdc-1; Gdc1; GPD-C; GPD1; Gpd3; GPDH; GPDH-C; HTGTI; Kiaa4010; mKIAA4010
UniProt ID: (Human) P21695, (Mouse) P13707, (Rat) O35077
Entrez Gene ID: (Human) 2819, (Mouse) 14555, (Rat) 60666
gluconeogenesis
glycerophosphate shuttle
phosphatidic acid biosynthetic process
triglyceride biosynthetic process
positive regulation of glycolytic process
glycerol-3-phosphate catabolic process
cellular response to cAMP
cellular response to tumor necrosis factor
carbohydrate metabolic process
glycerol-3-phosphate metabolic process
NADH oxidation
NADH metabolic process
glycerolipid metabolic process
oxidation-reduction process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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