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Invitrogen
GPI Polyclonal Antibody
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Product Details
PA5-84103
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GPI. Recombinant protein control fragment (Product #RP-104938).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VINIGIGGSD LGPLMVTEAL KPYSSGGPRV WYVSNIDGTH IAKTLAQLNP ESSLFIIASK TFTTQETITN AETAKEWFLQ AAKDPSAVAK HFVALST
Highest antigen sequence indentity to the following orthologs: Rat - 96%, Mouse - 93%.
Target Information
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AMF; Autocrine motility factor; D-hexose-6-phosphate anomerase; Glucose-6-phosphate C2-epimerase; Glucose-6-phosphate isomerase; GPI; hexose monophosphate isomerase; hexosephosphate isomerase; Neuroleukin; NLK; oxoisomerase; PGI; PHI; Phosphoglucose isomerase; phosphohexomutase; Phosphohexose isomerase; phosphosaccharomutase; SA-36; sperm antigen; Sperm antigen 36; sperm antigen-36; unnamed protein product
Gene Aliases: AMF; CNSHA4; GNPI; GPI; NLK; PGI; PHI; SA-36; SA36
UniProt ID: (Human) P06744
Entrez Gene ID: (Human) 2821
in utero embryonic development
mesoderm formation
positive regulation of immunoglobulin production
carbohydrate metabolic process
fructose 6-phosphate metabolic process
gluconeogenesis
glycolytic process
humoral immune response
signal transduction
hemostasis
learning or memory
positive regulation of endothelial cell migration
response to estradiol
response to progesterone
response to testosterone
erythrocyte homeostasis
response to immobilization stress
response to muscle stretch
glucose homeostasis
negative regulation of apoptotic process
response to cadmium ion
glucose 6-phosphate metabolic process
canonical glycolysis
carbohydrate derivative metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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