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Invitrogen
GPI Polyclonal Antibody
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Product Details
PA5-97517
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Glucose-6-phosphate isomerase protein (2-554AA)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AMF; Autocrine motility factor; D-hexose-6-phosphate anomerase; glucose phosphate isomerase 1 complex; glucose phosphate isomerase 1, regulatory; glucose phosphate isomerase 1, structural; glucose phosphate isomerase 1, temporal; Glucose-6-phosphate C2-epimerase; Glucose-6-phosphate isomerase; GPI; hexose monophosphate isomerase; hexosephosphate isomerase; maturation factor; Neuroleukin; NLK; oxoisomerase; PGI; PHI; Phosphoglucose isomerase; phosphohexomutase; Phosphohexose isomerase; phosphosaccharomutase; SA-36; sperm antigen; Sperm antigen 36; sperm antigen-36; unnamed protein product
Gene Aliases: AMF; CNSHA4; GNPI; GPI; Gpi-1; Gpi-1r; Gpi-1s; Gpi-1t; Gpi1; Gpi1-r; Gpi1-s; Gpi1-t; Gpi1s; MF; NK; NK/GPI; NLK; Org; PGI; PHI; SA-36; SA36
UniProt ID: (Human) P06744, (Mouse) P06745
Entrez Gene ID: (Human) 2821, (Mouse) 14751
in utero embryonic development
mesoderm formation
positive regulation of immunoglobulin production
carbohydrate metabolic process
fructose 6-phosphate metabolic process
gluconeogenesis
glycolytic process
humoral immune response
signal transduction
hemostasis
learning or memory
positive regulation of endothelial cell migration
response to estradiol
response to progesterone
response to testosterone
erythrocyte homeostasis
response to immobilization stress
response to muscle stretch
glucose homeostasis
negative regulation of apoptotic process
response to cadmium ion
glucose 6-phosphate metabolic process
canonical glycolysis
carbohydrate derivative metabolic process
angiogenesis
methylglyoxal biosynthetic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of neuron apoptotic process
aldehyde catabolic process
glycolytic process through glucose-6-phosphate
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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