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Invitrogen
GPR125 Polyclonal Antibody
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FIGURE: 1 / 1
GPR125 Antibody (PA5-120377) in WB
Western blot analysis of GPR125 in extracts of Mouse liver. Samples were incubated with GPR125 Polyclonal antibody (Product # PA5-120377) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3 min.
Product Details
PA5-120377
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 370-600 of human ADGRA3 (NP_660333.2).
Conjugate
Form
Liquid
Concentration
1.2 mg/mL
Amount
120 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: Mouse liver. The target is usually found in the following locations: Membrane, Multi-pass membrane protein.
Immunogen sequence: ITAYLQCTRN THGSGIYPGN PQDERKAWRR CDRGGFWADD DYSRCQYAND VTRVLYMFNQ MPLNLTNAVA TARQLLAYTV EAANFSDKMD VIFVAEMIEK FGRFTKEEKS KELGDVMVDI ASNIMLADER VLWLAQREAK ACSRIVQCLQ RIATYRLAGG AHVYSTYSPN IALEAYVIKS TGFTGMTCTV FQKVAASDRT GLSDYGRRDP EGNLDKQLSF KCNVSNTFSS L
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and the LN-TM7 subfamily. Considered a novel orphan adhesion-type G-protein-coupled receptor, GPR125 has five leucine rich repeats (LRR), an immunoglobulin (Ig) domain and a GPS domain. GPR125 may play a functional role in choroidal and hippocampal response to brain injury. It is also suggested that GPR125 may be a marker for spermatogonial stem cells. Four isoforms of GPR125 exists due to alternative splicing events.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adhesion G protein-coupled receptor A3; G protein-coupled receptor 125; G-protein coupled receptor 125; probable G-protein coupled receptor 125
Gene Aliases: 3830613O22Rik; Adgra3; AU044632; Gpr125; Tem5-like
UniProt ID: (Mouse) Q7TT36
Entrez Gene ID: (Mouse) 70693, (Rat) 305408
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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