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Invitrogen
GPR3 Polyclonal Antibody
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Product Details
PA5-33689
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Hamster,
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 15 amino acid peptide from 2nd extracellular domain of human GPR3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster (100%) Rabbit (93%) Bovine, Panda, Pig (80%).
Target Information
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1, 000 members and is the largest known class of molecular targets with proven therapeutic value. GPR3 is an orphan receptor with constitutive G signaling activity. GPR3 modulates a number of brain functions, including behavioral responses to stress, neurite outgrowth and amyloid-beta peptide generation suggesting that it may play a role in Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACCA orphan receptor; adenylate cyclase constitutive activator; G protein-coupled receptor 3; G protein-coupled receptor R4; G-protein coupled receptor 3; G-protein-coupled receptor R4; GPCR21; Hacca; OTTHUMP00000043209; unnamed protein product
Gene Aliases: ACCA; Gpcr20; Gpcr21; Gpcr3; GPR3; I79_019963
UniProt ID: (Human) P46089, (Mouse) P35413, (Rat) Q8K1Q3
Entrez Gene ID: (Human) 2827, (Mouse) 14748, (Rat) 266769, (Chinese hamster) 100759546
sphingosine-1-phosphate signaling pathway
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
regulation of meiotic nuclear division
positive regulation of cold-induced thermogenesis
positive regulation of cytosolic calcium ion concentration
positive regulation of cAMP metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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