The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
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Protein Aliases: Adapter protein GRID; GADS protein; GRB-2-like protein; GRB-2-related monocytic adapter protein; GRB2-related adapter protein 2; Grb2-related adaptor downstream of Sch; GRB2-related adaptor protein 2; GRB2-related protein with insert domain; GRB2L; GRBLG; GRBX; Grf-40; Grf40 adapter protein; Growth factor receptor-binding protein; growth factor receptor-bound protein 2-related adaptor protein 2; Hematopoietic cell-associated adapter protein GrpL; Hematopoietic cell-associated adaptor protein GrpL; MONA; monocytic adapter; monocytic adaptor; P38; Protein GADS; RP3-370M22.1; SH3-SH2-SH3 adapter Mona; SH3-SH2-SH3 adaptor molecule
Gene Aliases: GADS; GRAP-2; GRAP2; GRB2L; GRBLG; GrbX; Grf40; GRID; GRPL; Mona; P38